Roswell Park Comprehensive Cancer Center

Roswell Park Comprehensive Cancer Center was founded in 1898 as the world’s first cancer research center. From our early breakthroughs in chemotherapy to the discovery of the PSA biomarker, Roswell Park has continually shaped the way cancer is diagnosed, treated, and prevented worldwide.

As one of the nation’s first NCI-designated Comprehensive Cancer Centers, Roswell Park is recognized with the highest rating of “Exceptional” by the National Cancer Institute. We are consistently ranked among the top cancer hospitals in the country by U.S. News & World Report and are widely regarded for our leadership in immunotherapy, cellular therapies, and translational research.

Our reputation is built not only on discovery but also on compassion. We are known as a place where cutting-edge medicine and human-centered care come together, giving patients confidence and comfort during life’s most challenging moments.

Roswell Park by the numbers:

• Founded: 1898 — the first dedicated cancer research institute in the world
• Employees: 4,000+
• Faculty: 400+ physicians and researchers
• Nurses: 1000. Roswell Park nurses and nurse practitioners have achieved Magnet® recognition and Oncology Nursing Society (ONS) certification—demonstrating the highest standards of excellence in cancer nursing. Their expertise and dedication ensure every patient receives compassionate, world-class care.
• Patients Served: 100,000+ outpatient visits annually
• Research: $100M+ in annual external funding
• Clinical Trials: 400+ active trials at any given time, spanning early-phase to late-stage interventions
• Immunotherapy program: Through the Roswell Park Empire State Consortium and its state-of-the-art 20-room GMP facility, Roswell Park is accelerating the development and manufacturing of innovative cell and gene therapies to bring tomorrow’s treatments to patients today.
• Special recognition: One of just 56 NCI-designated comprehensive cancer centers nationwide, and the only one in Upstate New York
• Survivorship & Supportive Care: Nationally recognized programs serving tens of thousands of cancer survivors

Major milestones include being the first center to administer chemotherapy, the development of the prostate-specific antigen (PSA) test, and ongoing leadership in vaccine and immunotherapy development.

Roswell Park is structured to ensure collaboration across research and clinical domains:

• Executive Leadership: Led by the President & CEO, supported by a Physician in Chief, Deputy Director of Science, Chief Medical Officer, and Chief Nursing Officer.
• Research Programs: Cancer Genetics and Genomics, Cell Stress Biology, Immunology, Pharmacology & Therapeutics, Cancer Prevention and Control, Health Behavior and Biostatistics and Bioinformatics
• Clinical Departments: Cover all major oncology subspecialties including Surgical Oncology, Medical Oncology, Radiation Oncology, Pediatrics, Hematology, Urology, Gynecologic Oncology, Thoracic Surgery, and Neurosurgery.

This integrated model allows physicians to collaborate seamlessly with researchers, ensuring discoveries move rapidly from bench to bedside.

Roswell Park maintains a long-standing academic affiliation with the University at Buffalo Jacobs School of Medicine and Biomedical Sciences. This partnership provides:

• Faculty appointments. Most Roswell Park physicians hold academic titles through UB.
• Teaching opportunities. Engage with medical students, residents, and fellows across a wide range of oncology specialties.
• Mentorship & leadership. Physicians can shape the next generation of oncologists and researchers through structured training programs.
• Dual career paths. Clinician-scientists benefit from access to both Roswell Park’s research infrastructure and UB’s academic resources.
• Extensive resident and fellowships program across disciplines from the University at Buffalo and University of Rochester.

At Roswell Park, physicians practice in a high-volume, tertiary referral center that draws patients from across New York State, the Northeast, and beyond. Our reputation as the region’s only NCI-designated Comprehensive Cancer Center makes us the trusted destination for the most complex cancer cases.

• Referral Base. A strong and growing Roswell Park Care Network ensures steady referral volume and collaboration with community physicians.
• Advanced technologies. Access cutting-edge tools such as robotic surgery platforms, image-guided radiation therapy, CAR T-cell therapy, cellular and gene therapies, advanced imaging modalities, and minimally invasive surgical techniques.
• Multidisciplinary model. Physicians are supported by expert nurse practitioners, physician assistants, oncology nurses, pharmacists, dietitians, social workers, and patient navigators — ensuring every patient benefits from a team-based approach.

Roswell Park offers a robust environment where clinical care and scientific discovery are tightly integrated. Our infrastructure is designed to empower physician-investigators.

• Core facilities. Specialized labs in genomics, proteomics, flow cytometry, investigational drug support, pathology, gene targeting, and translational imaging.
• Biobank. One of the nation’s most comprehensive cancer biorepositories, supporting translational and population science research.
• Grants & funding support. A dedicated grants office provides assistance with NIH, DOD, and foundation proposals, with mentoring for early-career investigators.
• Clinical trial ecosystem. More than 400 active clinical trials with streamlined enrollment support, regulatory assistance, and data management.
• Collaboration across departments. Opportunities to partner with basic scientists, immunologists, and population health experts to translate discoveries into therapies.

Physicians at Roswell Park have a strong academic presence through our partnership with the University at Buffalo and the University of Rochester.

• Medical Education. Teach and mentor medical students, residents, and fellows in oncology subspecialties.
• Fellowship programs. Supervise and train subspecialty fellows in hematology/oncology, surgical oncology, and radiation oncology.
• Mentorship pathways. Structured mentorship opportunities for faculty at every stage of their careers, with programs focused on leadership, research productivity, and clinical excellence.

We believe that when physicians thrive, patients benefit. Roswell Park provides a supportive framework for professional growth.

• Promotion & tenure. Multiple career pathways with advancement opportunities through academic promotion at Roswell Park and University at Buffalo.
• Leadership development. Access to physician leadership programs, mentorship networks, and opportunities to shape institutional strategy.
• Conference support. CME allowance, protected time, and funding for travel to present research at national and international conferences.
• Continuing education. On-site CME programming, visiting professorships, and seminars to foster lifelong learning.

Living and working in Buffalo means being part of a vibrant, welcoming community with all the advantages of a major metropolitan area — without the high costs or congestion of larger cities.

• Affordable living. Buffalo consistently ranks among the most affordable cities in the U.S., with accessible housing options, short commutes, and a low cost of living.
• Education & schools. Families benefit from excellent private and public schools, as well as proximity to nationally recognized universities.
• Cultural amenities. Buffalo is home to a thriving arts scene, professional sports teams, renowned theaters, and the historic AKG Art Gallery.
• Outdoor recreation. Four seasons of recreation include waterfront trails, sailing on Lake Erie, skiing in the nearby Southern Tier, and the natural wonder of Niagara Falls just 20 minutes away.
• Regional connectivity. Easy travel access with an international airport and proximity to major U.S. and Canadian cities such as Toronto, New York, Cleveland and Pittsburgh.

At Roswell Park, we believe the health and wellness of our physicians is essential to delivering the best care to patients. We provide robust programs and resources to support your well-being, both inside and outside of the hospital.

• Physician wellness programs. Access to wellness coaching, peer support groups and stress management workshops.
• Mental health resources. Confidential counseling and mental health services are available to support resilience and work-life balance.
• Dual-career support. We recognize that career decisions often affect the whole family. Our recruitment team works closely with local institutions and employers to provide dual-career assistance for spouses and partners.
• Community integration. Relocation support, networking opportunities, and family-friendly events help new physicians settle quickly into the Buffalo community.