Danielle M. Enserro

Biography:

I am the Associate Director of Biostatistics in the Clinical Trials Development Division (CTDD) of the Department of Biostatistics & Bioinformatics. I am also an appointed Research Assistant Professor in both the Biostatistics & Bioinformatics Department at Roswell Park and the Department of Biostatistics within the School of Public Health & Health Professions at the State University of New York at Buffalo.

In my role as CTDD Associate Director of Biostatistics, I participate in the overall leadership and determination of the scientific direction of the CTDD. I also oversee the CTDD Statistical Programming Team, and I provide and maintain responsibility for statistical collaboration in various CTDD research areas. I design, maintain, and analyze a wide range of clinical studies in collaboration with research clinicians for NRG Oncology and the Gynecologic Oncology Group (GOG) Foundation. I am a certified SAS programmer and I also have experience with R, EAST and PASS.

Prior to beginning my current role, I served as a CTDD Biostatistician for over six years. My time within CTDD has produced more than 11 research publications, including one in NEJM. Most of my expertise is in endometrial, ovarian, and rare tumor cancers. I also work on cancer prevention and control clinical trials through the NRG Oncology NCORP Research Base. I serve as a committee member on several NRG Committees including the Rare Tumor Subcommittee, the NCORP Cancer Prevention and Control Committee, and the NCORP Patient Reported Outcomes Committee.

I received my PhD in Biostatistics from Boston University in 2017. My graduate research work focused on measures of discrimination, reclassification, and calibration for risk prediction modeling.  A portion of my dissertation was published in "Statistics in Medicine" in 2019. I received my MA in Biostatistics from Boston University in 2012 and my BA in Mathematical Science from Elms College in 2006.

During my time at Boston University and for several years afterwards, I worked extensively as a Research Scientist on cardiovascular analyses for the Framingham Heart Study. I contributed to more than 25 research publications in a 10-year span. My focuses included prognostic and predictive biomarker analysis, lifetime heart failure risk over the life course, trajectory modeling and temporal trend analysis, and several studies utilizing the Ideal Cardiovascular Health score.

I also serve as a statistical mentor for the BRIDGES Research Initiative for the Society of Gynecologic Oncology (SGO). I provide statistical mentorship and support to 30 mentees per cycle, and  also present on various statistical topics at meetings.  I have presented on several statistical topic areas including novel trial design and statistics for rare tumor trials, study design considerations for prevention trials, study designs for adaptive trials, and statistical challenges of immunotherapy trials.