Position #1 is focused on studying the role of retinoblastoma tumor suppressor pathway (RB, p16ink4a, and cyclin D1) in breast cancer. Specific emphasis will be placed on the role of RB loss in disease progression and therapeutic response. This work will incorporate the use of cell culture, animal models, and clinical specimens.
Position #2 is focused on deciphering mechanisms through which breast cancers evade standard therapies and elucidate new approaches for therapeutic intervention using targeted approaches. These studies will use PDX, organoid, and mouse models.
Ideal candidates will have experience with cancer research and have a track record of leading projects to publication. Fellows will be expected to direct independent projects in a multi-disciplinary setting, assist in mentoring junior lab members, and apply for independent fellowship funding.
Requirements:
1. PhD in a related discipline
2. Record of research accomplishment
3. Self motivated with a positive attitude
4. Strong interpersonal skills
5. Ability to write manuscripts and assemble relevant data
Interested candidates, please send CV and brief letter of interest to:
Erik Knudsen, PhD
Professor, Center for Personalized Medicine
Erik.Knudsen@RoswellPark.org