Postdoc positions are available immediately, in Dr. Dean Tang’s laboratory, to study NIH grant-supported projects that are centered on understanding prostate cancer cell heterogeneity/plasticity (Li Q et al., Nat. Commun. 2018; Zhang D et al., Nat. Commun. 2020; Kirk J. et al., Cell Stem Cell 2024) and the mechanisms of action of tumor suppressor LRIG1 (Li Q, et al., Nat. Commun. 10:5494, 2019; Ji Y. et al., Semin. Cancer Biol. 2022). The main ongoing projects include, among others: 1) investigating the tumor-suppressive functions of LRIG1 in novel genetic mouse models; 2) uncovering the novel LRIG1-interacting protein partners in both androgen-dependent and androgen-independent prostate cancers; 3) developing LRIG1-based biomarkers and therapeutics; and 4) elucidating the epigenetic underpinnings of treatment-induced plasticity in prostate cancer cells.
Potential candidates should have received solid Ph.D training in molecular biology and biochemistry as evidenced by high-quality peer-reviewed publications. Candidates with strong (prostate) cancer biology knowledge and working experience in genetically engineered mouse models (GEMMs) are strongly encouraged to apply and will be given priority considerations.
Suitable candidates should submit the NIH biosketch and/or full CV with the names of 3 referees to:
Dr. Dean Tang
Professor & Chair
Department of Pharmacology & Therapeutics
Roswell Park Comprehensive Cancer Center
Dean.Tang@RoswellPark.org