Specializing In:
- Surgical Oncology
Research Interests:
- Cancer genetics
- Sarcoma biology
- Clinical surgical outcomes
Biography
Dr. Seavey is one of the Complex Surgical Oncology Fellows at Roswell Park. He completed his undergraduate degree in Biology followed by his MD from The George Washington University. He went on to the Cleveland Clinic for his residency in General Surgery. During his professional development time, he obtained his PhD in Molecular Medicine at Case Western Reserve University with a focus on Sarcoma Biology under the direction of Dr. Brian Rubin.
His PhD research focused on the understanding the underlying mechanisms driving tumorigenesis in a rare vascular sarcoma, Epithelioid Hemangioendothelioma. His clinical interests include gastric, small bowel, retroperitoneal, and peritoneal surface malignancies.
Positions
Roswell Park Comprehensive Cancer Center
- Surgical Oncology Fellow
- Department of Surgical Oncology
Background
Education and Training
- 2019-2022 - PhD - Molecular Medicine, Case Western Reserve University, Cleveland OH
- 2013-2017 - MD - The George Washington University, Washington DC
Residency
- 2017-2025, Cleveland Clinic, General Surgery
Professional Memberships
- Society of Surgical Oncology
- American College of Surgeons
Honors & Awards
- 2022, EHE Foundation Travel Fellowship Grant, EHE Foundation
- 2022, Lower Award (Non-Clinical Research Category), Cleveland Clinic
- 2020-2022, Crile Research Fellowship Award, Cleveland Clinic
- 2021 CRAVAT Foundation Travel Fellow, CRAVAT Foundation
- 2020-2021 Crile Travel Fellowship Award, Cleveland Clinic
- 2018-2023 ABSITE Award
- 2018-2023 Outstanding Clinical Preceptor, Cleveland Clinic Lerner School of Medicine
- 2017 Paul L. DeWitt Award in Surgery, The George Washington University
- 2016 Alpha Omega Alpha Medical Honors Society, The George Washington University
- 2014-2017 Dr. Domenick J. Sisto Scholarship, The George Washington University
- 2013-2017 Tauber Holocaust Memorial Scholarship for Medicine, The George Washington University
- 2013 Phi Beta Kappa Society, The George Washington University
- 2013 Summa Cum Laude, The George Washington University
Publications
Full Publications list on PubMed
- Seavey, C.N., Hallett, A., Li, S., Che, K., Pobbati, A.V., Ma, S., Burtscher, A., Kanai, R., Lamar, J.M., Rubin, B.P., 2023. Loss of CDKN2A Cooperates with WWTR1(TAZ)-CAMTA1 Gene Fusion to Promote Tumor Progression in Epithelioid Hemangioendothelioma. Clin Cancer Res 29, 2480–2493. https://doi.org/10.1158/1078-0432.CCR-22-2497
- Seavey, C.N., Pobbati, A.V., Rubin, B.P., 2022. Unraveling the Biology of Epithelioid Hemangioendothelioma, a TAZ–CAMTA1 Fusion Driven Sarcoma. Cancers 14. https://doi.org/10.3390/cancers14122980
- Seavey, C.N., Pobbati, A.V., Hallett, A., Ma, S., Reynolds, J.P., Kanai, R., Lamar, J.M., Rubin, B.P., 2021. WWTR1(TAZ)-CAMTA1 gene fusion is sufficient to dysregulate YAP/TAZ signaling and drive epithelioid hemangioendothelioma tumorigenesis. Genes Dev 35, 512–527. https://doi.org/10.1101/gad.348220.120
- Wehrle, C.J., Seavey, C.N., Chang, J., Stackhouse, K., Woo, K., Augustin, T., Joyce, D., Simon, R., Walsh, R.M., Naffouje, S.A., 2023. Neoadjuvant Gastric Score: How Response to Neoadjuvant Chemotherapy Affects Overall Survival and Adjuvant Benefit. Ann Surg Oncol 30, 7240–7250. https://doi.org/10.1245/s10434-023-14259-9
- Ma, S., Kanai, R., Pobbati, A.V., Li, S., Che, K., Seavey, C.N., Hallett, A., Burtscher, A., Lamar, J.M., Rubin, B.P., 2022. The TAZ-CAMTA1 fusion protein promotes tumorigenesis via connective tissue growth factor and Ras-MAPK signaling in epithelioid hemangioendothelioma. Clin Cancer Res clincanres.0421.2022. https://doi.org/10.1158/1078-0432.CCR-22-0421