Metastasis, or the spread of cancer from one site in the body to another, remains a leading cause of cancer-related deaths. Understanding how solid tumors spread is crucial to the effort to improve patient outcomes. A team of scientists led by Scott Abrams, PhD, at Roswell Park Comprehensive Cancer Center uncovered a pathway associated with metastases to the lung, a common site for cancer spread. The work, just published in the journal JCI Insight, has potentially significant implications that may point the way to new cancer therapies.