Deficiency in ST6GAL1, one of the two α2,6-sialyltransferases, has only a minor effect on the pathogenesis of prion disease
- Publication: Frontiers in Molecular Biosciences, November 2022
- Authors: Makarava N, Katorcha E, Chang JC, Lau JTY, Baskakov IV
- Citation: Front Mol Biosci. 2022 Nov 14;9:1058602.
Extracellular sialyltransferase ST6GAL1 in breast tumor cell growth and invasiveness
- Publication: Cancer Gene Therapy (Nature), November 2022
- Authors: Hait NC, Maiti A, Wu R, Andersen VL, Hsu CC, Wu Y, Chapla DG, Takabe K, Rusiniak ME, Bshara W, Zhang J, Moremen KW, Lau JTY
- Citation: Cancer Gene Ther. 2022 Nov;29(11):1662-1675
- Rusiniak ME, et al. Extracellular ST6GAL1 regulates monocyte-macrophage development and survival. Glycobiology. 2022 Jul 13;32(8):701-711.
- Erickson JJ, et al. Pregnancy enables antibody protection against intracellular infection. Nature. 2022 Jun;606(7915):769-775.
- Irons EE, et al. Bacterial colonization and TH17 immunity are shaped by intestinal sialylation in neonatal mice. Glycobiology. 2022 Apr 21;32(5):414-428.
- Punch PR, et al. The sialyltransferase ST6GAL1 protects against radiation-induced gastrointestinal damage. Glycobiology. 2020 Jul 20;30(7):446-453. doi: 10.1093/glycob/cwz108. PMID: 31897489; PMCID: PMC7305799.
- Weinstock NI, et al. Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction. Neuron. 2020 Jul 8;107(1):65-81.e9.
- Irons EE, Punch PR, Lau JTY. Blood-Borne ST6GAL1 Regulates Immunoglobulin Production in B Cells. Front Immunol. 2020 Apr 23;11:617.
- Nasirikenari M, et al. Recombinant Sialyltransferase Infusion Mitigates Infection-Driven Acute Lung Inflammation. Front Immunol. 2019 Feb 4;10:48.
- Irons EE, Lau JTY. Systemic ST6Gal-1 Is a Pro-survival Factor for Murine Transitional B Cells. Front Immunol. 2018 Sep 20;9:2150.
- Zhang C, et al. The physical spacing between the von Willebrand factor D'D3 and A1 domains regulates platelet adhesion in vitro and in vivo. J Thromb Haemost. 2018 Mar;16(3):571-582.
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Roswell Park Comprehensive Cancer Center
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