Available Clinical Trials

To inquire about participating in these studies, call 1-800-ROSWELL (1-800-767-9355). E-mail: askroswell@roswellpark.org
 

A Study of PARG Inhibitor IDE161 in Participants with Advanced Solid Tumors ( IDE161-001)

Principal Investigator: Fountzilas, Christos

A Phase 1 (First-In-Human [FIH]), Multi-Site, Dose Escalation and Expansion Study of WTX-330 in Adult Patients with Advanced or Metastatic Solid Tumors or Lymphoma

Principal Investigator: Fountzilas, Christos

A COMBOMATCH TREATMENT TRIAL: PALBOCICLIB AND BINIMETINIB IN RAS-MUTANT CANCERS NCI-supplied agent(s): Palbociclib (NSC #772256); Binimetinib (NSC #788187)

Principal Investigator: Levine, Ellis G

Phase I/IIa Clinical Trial Evaluating the Safety and Efficacy of Rintatolimod Combined with IFN alpha2b (Bioferon®) to Enhance the Effectiveness of Pembrolizumab in Patients with Metastatic Triple Negative Breast Cancer

Principal Investigator: Krishnamurthy, Anuradha

Interim FDG-PET/CT for PreDIcting REsponse of HER2+ Breast Cancer to Neoadjuvant Therapy: DIRECT trial

Principal Investigator: Levine, Ellis G

NRG-BR009: A Phase III Adjuvant Trial Evaluating the Addition of Adjuvant
Chemotherapy to Ovarian Function Suppression plus Endocrine Therapy
in Premenopausal Patients with pN0-1, ER-Positive/HER2-Negative Breast Cancer
and an Oncotype Recurrence…

Principal Investigator: Levine, Ellis G

A Multicenter Phase I/Ib Dose Escalation Study of WTX-124 as Monotherapy and in Combination with Pembrolizumab in Patients with Selected Advanced or Metastatic Solid Tumors

Principal Investigator: Puzanov, Igor

A012103: OPTIMICE-PCR: DE-ESCALATION OF THERAPY IN EARLY-STAGE TNBC PATIENTS WHO ACHIEVE PCR AFTER NEOADJUVANT CHEMOTHERAPY WITH CHECKPOINT INHIBITOR THERAPY

Principal Investigator: Levine, Ellis G

A Phase IIA Trial Assessing the Tolerability of Abemaciclib in Combination with
Endocrine Therapy in Patients Age 70 and Older with Hormone Receptor Positive
Metastatic Breast Cancer Who Have Progressed on or After Prior CDK 4/6 Inhibition

Principal Investigator: Levine, Ellis G

Respiratory Muscle Training During Breast Cancer Treatment: Effects on the Autonomic Nervous System and Cardiotoxicity

Principal Investigator: Ray, Andrew D

A Phase IIa Study of Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab in Patients with Asymptomatic Brain Metastasis from Triple Negative Breast Cancer (TNBC) or HER2+ Breast Cancer (HER2+BC)

Principal Investigator: Krishnamurthy, Anuradha

NRG-BR007: A PHASE III CLINICAL TRIAL EVALUATING DE-ESCALATION OF BREAST RADIATION FOR CONSERVATIVE TREATMENT OF STAGE I, HORMONE SENSITIVE, HER2-NEGATIVE, ONCOTYPE RECURRENCE SCORE ≤ 18 BREAST CANCER

Principal Investigator: Fung-Kee-Fung, Simon

Photoacoustic Imaging of Human Breast

Principal Investigator: Bonaccio, Ermelinda

(S1706) A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy versus Radiotherapy Alone for Inflammatory Breast Cancer

Principal Investigator: Fung-Kee-Fung, Simon

(A011801) The COMPASSHER2 Trials (COMprehensive Use of Pathologic Response ASSessment to Optimize Therapy in HER2-Positive Breast Cancer): COMPASSHER2 Residual Disease (RD), A Double-Blinded, Phase III Randomized Trial of T-DM1 and Placebo Compared with…

Principal Investigator: Levine, Ellis G