Biomedical Research Informatics Shared Resource (BRISR)

Clinical data management and delivery for research

Clinical Data Management and Delivery for Research: We provide structured access to real-time reliable clinical data for the advancement of non-interventional studies at Roswell Park. Data is delivered in a HIPAA-compliant manner and we ensure that all regulations and data safety standards are met to ensure our patient’s privacy. The BRISR team also works closely with Roswell Park biobanks to annotate biospecimens and facilitate the process for patient cohort identification and case selections. Our access to detailed clinical data can be paired with tissue samples from the Pathology Network Shared Resource or blood samples from the Data Bank and BioRepository (DBBR) Shared Resource while supporting the data needs for investigators working in preclinical subject research efforts.

Specific services we offer:

• Clinical data requests
• Cohort selection
• REDCap survey/data design
• Honest Broker services
• Grant application support
• Data standardization and harmonization

Custom Software Development for Research

We work with researchers to develop and implement custom tools and databases to streamline the collection, organization, validation, analysis, and visualization of data. This allows for streamlined processes that aid in the advancement of scientific understanding or efficiency. We also work with Research IT to develop computational platforms to support the broader institutional goals. Examples include the international Stacey Scott Lung Cancer Registry database, the nSight platform for searching the de-identified clinical data at Roswell Park, the REVEAL project for parsing and querying pathology reports, and the VisPortal for visualizing Roswell Park single-cell genomics data.

Artificial intelligence analysis for clinical and bioinformatics research

We provide collaborative research consultations and services for machine and deep learning solutions for clinical and bioinformatics research. Our goal is to develop through team science artifical intelligence and high throughput computational methods that elevate Roswell Park’s research programs and provide meaningful clinical and biological insights. Our staff is trained in statistical and computational artificial intelligence and can provide insights into cutting-edge methodology.

Clinical data available for researchers:

• Cancer registry: Tumors diagnosed and treated here at Roswell Park are kept in a registry, providing access to basic tumor information, treatment and first recurrence details.
• Electronic health record: Includes drug treatment at Roswell Park, patient vitals (height, weight, BMI, blood pressure, etc), visits, orders (scans, scopes, tests, etc.), comorbidities and family history.
• Finance database: Billing data which helps to identify procedures, treatments and other information for each patient.
• Cerner lab results: Information from blood and other laboratory tests completed at Roswell Park such as urinalysis and cultures.
• OmniSeq and Foundation Medicine results: Outcomes from all clinically ordered panels such as the OmniSeq Comprehensive Panel and the Immune Report Card.

Frequently asked questions

Publications