Mark Hennon, MD, FACS

Specialty: Thoracic Surgery
Director, Thoracic Surgery Training Program
Vice Chair, Department of Thoracic Surgery

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Locations
Dr. Hennon is a Buffalo Spree Top Doctor! Top Doctors 2026 See all of our physicians who made this year's list.

Cancers Treated:

Carcinoid Esophageal Lung Mediastinal Mesothelioma Thymus

Specializing In:

  • Minimally invasive surgery and endoscopy for the diagnosis, staging and palliation of oncologic diseases of the thorax

Research Interests:

  • Minimally invasive surgical approaches for complex lung Tumor Resection
  • Impact of minimally invasive thoracic surgery approaches on short- and long-term outcomes for patients being treated for lung cancer

Positions

Roswell Park Comprehensive Cancer Center

  • Associate Professor of Oncology
  • Director, Thoracic Surgery Training Program
  • Vice Chair – Department of Thoracic Surgery

Jacobs School of Medicine and Biomedical Sciences, University at Buffalo

  • Associate Professor of Surgery - Department of Surgery

Background

Education and Training

  • 2002 - MD - State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, NY
  • 1998 - BS with Honors in Chemistry, summa cum laude - Westminster College, New Wilmington, PA

Residency

  • 2010 - Cardiothoracic Surgery Resident, University of Wisconsin Hospital and Clinics, Madison, WI
  • 2007-2008 - Executive Chief Resident - Allegheny General Hospital
  • 2006 - Clinical Research Resident - Allegheny General Hospital
  • 2003- 2005, 2006-2008 - General Surgery Resident, Allegheny General Hospital, Pittsburgh, PA

Fellowship

  • 2011 - Thoracic Surgical Oncology/Minimally Invasive Fellowship Roswell Park Comprehensive Cancer Center

Board Certification

  • American Board of Surgery
  • American Board of Thoracic Surgery

Professional Memberships

  • Society of Thoracic Surgery
  • Association for Academic Surgery

Honors & Awards

  • 2013 - 1st place, University at Buffalo Department of Surgery Outstanding Faculty Teacher
Do pollution, asbestos and radon cause lung cancer? How lung cancer screening saved Tina's life Advocating for lung cancer screening: Colleen’s story Surviving a Pancoast tumor: Mark’s story

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Publications

1. Hennon M, Groman A, Kumar A, Castaldo L, George S, Demmy T, Attwood K, Yendamuri S. Correlation between perioperative outcomes and long-term survival for non-small lung cancer treated at major centers. J Thorac Cardiovasc Surg. 2020 Dec 3:S50022-5223(20)33194-9. PMID:33451832

2. Hennon MW, DeGraaff LH, Groman, A, Demmy TL, Yendamuri S. The Association of Nodal Upstaging with Surgical Approach and Its Impact on Long-term Survival After Resection of Non-small Cell Lung Cancer. Eur J Cardiothorac Surg. 2020 May 1:57(5):888-895. E-pub Nov. 25 2019 PMID: 31764992

3. Hennon MW, Kumar A, Devisetty H, D’Amico T, Demmy TL, Groman A, Yendamuri S. “Minimally Invasive Approaches do not Compromise Outcomes for Pneumonectomy, a Comparison Utilizing the National Cancer Database”. J Thorac Oncol. 2018 Oct 4. Pii: S1556-0864(18)33176-9. Doi:10.1016/j.jtho.2018.2018.09.024 [E-pub ahead of print]PMID:30292851

4. Hennon M, Landreneau RJ. Role of Segmentectomy in Treatment of Early-Stage Non-Small Cell Lung Cancer. Ann Surg Oncol. 2018 Jan;25(1):59-63. doi: 10.1245/s10434-017-5787-5. Epub 2017 Mar 1.

5. Miller JA, Groman A, Yendamuri S, Hennon M. “Radiation with Neoadjuvant Chemotherapy Does Not Improve Outcomes in Esophageal Squamous Cell Cancer”. J Surg Res. 2018 Dec 24;236:259-265. Doi: 10.1016/j.jss.2018.11.052. [Epub ahead of print] PMID: 30694764