Yuesheng Zhang, MD, PhD

Member and Professor of Oncology
Department of Pharmacology and Therapeutics
Department of Cancer Prevention and Control
Member, Developmental Therapeutics Program
Professor, Program of Molecular Pharmacology and Cancer Therapeutics
Roswell Park Comprehensive Cancer Center
Special Interests: 
Cancer chemoprevention
Chemopreventive activity and mechanism of action of dietary isothiocyanates
Molecular basis of gender disparity in bladder cancer risk
Novel functions of prolidase
Experimental therapeutics of EGFR- and/or HER2-positive cancer
Plasma-based protein degradation and intervention
Mechanism of p53 regulation


Dr. Yuesheng Zhang joined the faculty of Roswell Park Comprehensive Cancer Center in 2003 and has been a Professor of Oncology since 2007. He has also been a Professor of the Roswell Park Graduate Division, the State University of New York Graduate College since 2003. He came to Roswell Park from the University of Arizona, Arizona Cancer Center, where he served as an Assistant Professor of Medicine.

Dr. Zhang earned his M.D. in 1984 and M.S. in 1988 from Zhejiang University School of Medicine (Formerly Zhejiang Medical University, Hangzhou, China), and his Ph.D. in Pharmacology and Molecular Sciences in 1996 from the Johns Hopkins University School of Medicine (Baltimore, USA), where he also completed postdoctoral fellowship and served as a junior faculty member.

Dr. Zhang is a member of the American Association for Cancer Research (AACR) and the American Society of Biochemistry & Molecular Biology (ASBMB). Dr. Zhang is also a member of the editorial boards of Molecular Cancer Therapeutics, Molecular Nutrition and Food Research, and Journal of Carcinogenesis and Mutagenesis. He has served and continues to serve on many NIH study sections and AACR grant review panels.


Education and Training: 
PhD - Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD
MD - Zhejiang University School of Medicine, Hangzhou, China
MS - Pathophysiology, Zhejiang University School of Medicine, Hangzhou, China