Valerie Francescutti, MD, MSc, FACS, FRCSC
Valerie Francescutti, MD, MSc, FACS, FRCSC
I joined the Surgical Oncology faculty at Roswell Park Cancer Institute in 2012 as an Assistant Professor of Surgical Oncology in Soft Tissue and GI surgery.
I earned my medical degree from McMaster University, in Hamilton, Ontario, Canada. I then went on to complete a General Surgery residency at McMaster University, becoming certified in General Surgery by the Royal College of Physicians and Surgeons of Canada (2010) and the American Board of Surgery (2010). I completed my Surgical Oncology fellowship at Roswell Park Cancer Institute (2010-2012) with special interest in Soft Tissue and GI cancers, and regional therapies.
I am active in clinical research, specifically addressing knowledge translation strategies to improve cytoreduction/HIPEC practice and quality of surgical care. From a basic science and translational research perspective, I am interested in pre-clinical models of HIPEC to improve our understanding of current chemotherapies used in this procedure, and test novel chemotherapeutics for ultimate translation into clinical trials for patients.
I have a keen interest in the patient experience for those undergoing CS/HIPEC. As patients are becoming more empowered with knowledge and information, my current work involves designing tailored education pathway programs for patients regarding the specifics of the surgery and outcomes. In addition, I am dedicated to excellent perioperative outcomes for patients undergoing major surgical oncology procedures, creating pre-, peri-, and post-operative management pathways to standardize approach and have consistently good outcomes.
I am a member of the American College of Surgeons, Society of Surgical Oncology, American Society of Clinical Oncology, and Royal College of Physicians and Surgeons of Canada.
Francescutti V, Sanghera SS, Cheney RT, Miller A, Salerno K, Burke R, Skitzki JJ, Kane JM 3rd. 2015 Homogenous Good Outcome in a Heterogeneous Group of Tumors: An Institutional Series of Outcomes of Superficial Soft Tissue Sarcomas. Sarcoma; 2015:325049. doi: 10.1155/2015/325049. Epub 2015 Nov 8. PMID: 26633938
Gabriel E, Kukar M, Groman A, Alvarez-Perez A, Schneider J, Francescutti V. 2015. A Formal Palliative Care Service Improves the Quality of Care in Patients with Stage IV Cancer and Bowel Obstruction. Am J Hosp Palliat Care. Sep 15. pii: 1049909115603960. [Epub ahead of print] PMID: 26377552
Thirunavukarasu P, Talati C, Munjal S, Attwood K, Edge SB, Francescutti V. 2015. Effect of Incorporation of Pretreatment Serum Carcinoembryonic Antigen Levels Into AJCC Staging for Colon Cancer on 5-Year Survival. JAMA Surg. 2015 Aug;150(8):747-55. doi: 10.1001/jamasurg.2015.0871. PMID: 26083632
Francescutti V, Amin N, Cadeddu M, Eskicioglu C, Forbes S, Kelly S, Yang I, Tsai S, Coates A, Grubac V, Simunovic M. 2015. An Internet-Based Collaborative Cancer Conference for Rectal Cancer Influenced Surgeon Treatment Recommendations. Ann Surg Oncol. Jul;22(7):2143-50. doi: 10.1245/s10434-014-4216-2. Epub 2014 Nov 11. PMID: 25384703
Oxenberg J, Papenfuss W, Esemuede I, Attwood K, Simunovic M, Kuvshinoff B, Francescutti V. 2015. Multidisciplinary cancer conferences for gastrointestinal malignancies result in measureable treatment changes: a prospective study of 149 consecutive patients. Ann Surg Oncol. May;22(5):1533-9. doi: 10.1245/s10434-014-4163-y. Epub 2014 Oct 17. PMID: 25323473
Francescutti V, Coates A, Thabane L, Goldsmith CH, Levine MN, Simunovic M. 2013. Patterns of use and outcomes for radiation therapy in the Quality Initiative in Rectal Cancer (QIRC) trial. Can J Surg. Dec; 56(6):E148-53. PMID: 24284154
Haslinger M, Francescutti V, Attwood K, McCart JA, Fakih M, Kane JM 3rd, Skitzki JJ. 2013. A contemporary analysis of morbidity and outcomes in cytoreduction/hyperthermic intraperitoneal chemoperfusion. Cancer Med. 2013 Jun;2(3):334-42. doi: 10.1002/cam4.80. Epub 2013 Apr 16. PMID: 23930210
Francescutti V, Rivera L, Seshadri M, Kim M, Haslinger M, Camoriano M, Attwood K, Kane JM 3rd, Skitzki JJ. 2013. The benefit of intraperitoneal chemotherapy for the treatment of colorectal carcinomatosis. Oncol Rep. 2013 Jul;30(1):35-42. doi: 10.3892/or.2013.2473. Epub 2013 May 15. PMID: 23673557
Francescutti V, Miller A, Satchidanand Y, Alvarez-Perez A, Dunn KB. 2013. Management of bowel obstruction in patients with stage IV cancer: predictors of outcome after surgery. Ann Surg Oncol. 2013 Mar;20(3):707-14. doi: 10.1245/s10434-012-2662-2. Epub 2012 Sep 19. PMID: 22990648
Francescutti V, Khoury T, Kulkarni S. 2012. Foreign body reaction mimicking breast carcinoma in patient with stage IV ovarian cancer. Breast J. 2012 Sep;18(5):490-1. doi: 10.1111/j.1524-4741.2012.01285.x. Epub 2012 Aug 15. No abstract available. PMID: 22892054
Francescutti V, Skitzki JJ. 2012. Sarcomas and the immune system: implications for therapeutic strategies. Surg Oncol Clin N Am. 2012 Apr;21(2):341-55. doi: 10.1016/j.soc.2011.11.002. Epub 2011 Dec 16. Review. PMID: 22365524
Jarkowski A 3rd, Hare R, Francescutti V, Wilkinson N, Khushalani N. 2011. Case report of pneumatosis intestinalis secondary to sunitinib treatment for refractory gastrointestinal stromal tumor. Anticancer Res. 2011 Oct;31(10):3429-32. PMID: 21965757
Francescutti V, Farrokhyar F, Tozer R, Heller B, Lovrics P, Jansz G, Kahnamoui K. 2011. Primary tumor and patient characteristics in breast cancer as predictors of adjuvant therapy regimen: a regression model. Cancer Chemother Pharmacol. 2011 Sep;68(3):661-8. doi: 10.1007/s00280-010-1532-5. Epub 2010 Dec 2. PMID: 21125276
Francescutti V, Choy I, Biertho L, Goldsmith CH, Anvari M. 2009. Gastrectomy and esophagogastrectomy for proximal and distal gastric lesions: a comparison of open and laparoscopic procedures. Surg Innov. 2009 Jun;16(2):134-9. doi: 10.1177/1553350609336738. Epub 2009 May 25. PMID: 19468037
Francescutti V, Ellis AK, Bourgeois JM, Ward C. 2008. Acute acalculous cholecystitis: an unusual presenting feature of Churg-Strauss vasculitis. Can J Surg. 2008 Dec;51(6):E129-30. No abstract available. PMID: 19057725
Gauthier ML, Torretto C, Ly J, Francescutti V, O'Day DH. 2003. Protein kinase Calpha negatively regulates cell spreading and motility in MDA-MB-231 human breast cancer cells downstream of epidermal growth factor receptor. Biochem Biophys Res Commun. 2003 Aug 8;307(4):839-46. PMID: 12878187
Cunnane SC, Francescutti V, Brenna JT, Crawford MA. 2000. Breast-fed infants achieve a higher rate of brain and whole body docosahexaenoate accumulation than formula-fed infants not consuming dietary docosahexaenoate. Lipids. 2000 Jan;35(1):105-11. Review. PMID: 10695931
Cunnane SC, Francescutti V. 1999. Fatty acid profiles of maternal adipose tissue in relation to infant development. Br J Nutr. 1999 Oct;82(4):253-4. PMID: 10655972
Cunnane SC, Francescutti V, Brenna JT. Docosahexaenoate requirement and infant development. Nutrition. 1999 Oct;15(10):801-2. PMID: 10501301