Dr. Seshadri is a Professor of Oncology and Chairman of the Department of Oral Oncology/Dentistry and Maxillofacial Prosthetics at Roswell Park Comprehensive Cancer Center with adjunct appointments in the Department of Radiology at the University at Buffalo – School of Medicine and Biomedical Sciences. As the scientific director of TISR, Dr. Seshadri oversees all preclinical and translational imaging services and provides strategic direction for the resource. He has extensive experience in the use of imaging techniques including magnetic resonance imaging (MRI), optical imaging (fluorescence, bioluminescence), intravital microscopy, ultrasound and photoacoustic imaging techniques. Dr. Seshadri has published over 60 publications in high impact journals including Science, Nature Nanotechnology, Radiology, Molecular Imaging and Biology, MRI and MRM on the use of advanced imaging methods to study tumor biology, monitor therapeutic response and on the development of novel multifunctional and multimodal nanoparticles for image-guided therapy of cancer.
Dr. Spernyak is the Director of Operations and Technology for TISR and has faculty appointments within the Department of Cell Stress Biology at Roswell Park Comprehensive Cancer Center and in the Medical Physics Program at the University at Buffalo. Dr. Spernyak has a BS in Physics and PhD in Biophysics and joined the resource in 2001 shortly after its inception. As Director of Operations and Technology, he is responsible for optimizing imaging protocols and improving the efficiency of image acquisition and data analysis. He is also responsible for implementing new acquisition methods to meet the individual needs of research projects. Dr. Spernyak has co-authored over 30 peer-reviewed articles over a wide range on MR imaging techniques including spectroscopy, diffusion, dynamic contrast enhancement, contrast agent development and multi-modality co-registration.
Drs. Seshadri and Spernyak jointly address the research needs of investigators and provide their scientific expertise to enable the conduct of imaging research studies in a timely and cost-effective manner.
Technical Support Specialist