Small Molecule Screening Shared Resource Selected Publications

  • Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase. Zhang F, Patel DM, Colavita K, Rodionova I, Buckley B, Scott DA, Kumar A, Shabalina SA, Saha S, Chernov M, Osterman AL, Kashina A. Nat Commun. 2015 Jul 15; 6:7517.
  • Antoch MP, Chernov MV. Pharmacological modulators of the circadian clock as potential therapeutic drugs. Mutat Res. 2009 Nov-Dec; 680(1-2):109-15. PMID: 20336820.
  • Hu Y, Spengler ML, Kuropatwinski KK, Comas-Soberats M, Jackson M, Chernov MV, Gleiberman AS, Fedtsova N, Rustum YM, Gudkov AV, Antoch MP. Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1. Oncotarget. 2011 Dec;2(12):1279-90. PMID: 22249125
  • Saha S, Wang J, Buckley B, Wang Q, Lilly B, Chernov M, Kashina A. Small molecule inhibitors of arginyltransferase regulate arginylation-dependent protein degradation, cell motility, and angiogenesis. Biochem Pharmacol. 2012 Apr 1; 83(7):866-73. Epub 2012 Jan 18. PMID: 22280815
  • Wei Luo, Wei-Dong Yu, Yingyu Ma, Mikhail Chernov, Donald L. Trump and Candace S. Johnson Inhibition of protein kinase CK2 reduces CYP24A1 expression and enhances 1,25-dihydroxyvitamin D3 anti-tumor activity. Cancer Res. 2013 Apr 1; 73(7):2289-97. PMID: 23358686