Bioactive Libraries

Historical libraries are collections of pre-existing organic compounds from different chemical labs selected based on their “drug-likeness”, and collections of pharmacological, bioactive or natural compounds. These libraries can be used for drug discovery as well as for “proof of principle” and assay validation experiments.

The Small Molecule Screening Shared Resource owns four historical libraries of known bioactive compounds:

These are the libraries of pharmacological compounds dissolved in DMSO, in 10 mM or 1mM concentration (MW is < 500). These libraries include FDA and internationally approved drugs, and bioactive and natural compounds with described biological activity.