Nicotine and Tobacco Product Assessment Equipment

Waters Xevo® TQ-XS Tandem Mass Spectrometer with ACQUITY UPLC I-Class Chromatography System (LC-MS/MS)

Xevo® TQ-XS MS/MS system provides low levels of ultimate sensitivity for detection of tobacco exposure biomarkers. It allows for precise measuring of biomarkers of exposure not only among conventional and novel tobacco product users but also among bystanders passively exposed to tobacco smoke. The system also provides high levels of reliability, reproducibility, and performance.

Agilent Technologies 7890B Gas Chromatograph/ 7250 Quadrupole Time-of-Flight Mass Spectrometry (GC-QTOF)

The Agilent 7250 Quadrupole Time-of-Flight GC/MS system delivers full-spectrum, high-resolution, accurate-mass data with a wide dynamic range for identifying, quantifying and investigating GC-amenable compounds.

Agilent Technologies 7890B Gas Chromatograph/ 5977A Mass Spectrometer (GC-MS)

The 5977A MSD includes a new, highly sensitive Extractor Ion Source for higher Signal-to-Noise (SNR) and a statistically based, low-femtogram Instrument Detection Limit (IDL). In combination, the 7890B/5977A GC/MSD delivers value in many ways: increased sample throughput, expanded analytical capabilities, reduced maintenance and decreased the cost for energy and gases.

Agilent Technologies 7890B Gas Chromatograph equipped with nitrogen-phosphorous detector (GC-NPD)

The Agilent Technologies 7890B is a gas chromatograph with a nitrogen-prosperous detector. This machine uses a hydrogen carrier gas along with fast oven cool-down, new backflush capabilities, and advanced automation features to help you get more done in less time, at the lowest possible cost per sample.

Perkin-Elmer PinAAcle 900Z Graphite Furnace Atomic Absorption Spectrometer (AAS)

AAS spectrometer is capable of ppb-level detection of elemental components of samples. Features longitudinal Zeeman background correction, transversely heated graphite atomizer (THGA), and stabilized temperature platform furnace (STPF). The spectrometer is also equipped with Perkin-Elmer Titan MPS microwave digestion system (for sample preparation).

Borgwaldt LX1 Single-Port Smoking Machine

This machine is equipped with:

  • Adjustable puff volume 5-200 ml, puff intervals 10-9999 sec and puff duration 1-4 sec
  • Testing system for tobacco and electronic cigarettes analysis
  • Trapping options include: Cambridge filters, impinger trapping set, solid-phase trapping tubes

Borgwaldt S1000 Shisha Smoker

  • Testing system for water pipe analysis, with an adjustable puff volume of 5-1375 ml
  • Trapping options include: Cambridge filters, impinger trapping set, solid-phase trapping tubes

Borgwaldt PV10 and KC-3 ventilation and pressure drop tester

The Borgwaldt PV10 and KC-3 are used to measure filter ventilation, the percentage of smoke that is diluting air when a smoker takes a puff, and pressure drop, the power required to move air through a whole cigarette. Filter ventilation impacts smoke composition, filter efficiency, and physical properties of smoke. Cigarette elasticity is highly dependent on filter ventilation. Pressure drop is a component of draw resistance, which contributes to smokers’ acceptance. These units are supplied with a certificate of exact flow rate, state-of-the-art touch-screen interface, and built-in fuse protection and quick connects.

Cerulean PPM-1000 paper porosity tester

Paper porosity is a measure of the movement of air through the wrapping paper surrounding the cigarette. The Cerulean PPM 1000M is used to take this measure utilizing both vacuum and pressure methods. It is capable of measuring the entire portfolio of tobacco papers across the whole measurement range 0.1- 40,000 CORESTA units. Operation is kept simple with easy-to-load paper clamps, a touch-screen interface and intuitive software that captures and displays the results.

30-Port Automatic Cigarette and E-Cigarette Smoking Machine JB2090

CH Technologies' JB2090 offers a highly versatile cigarette and e-cigarette smoking machine designed with significant flexibility so that it can be tailored to support a wide range of in vivo and in vitro exposure studies as well as cigarette smoke and vapor analytical applications.

E-Cigarette Aerosol Generator ECAG

E-Cigarette Aerosol Generator (ECAG) made by e~Aerosols has been designed and developed at NYU School of Medicine. It generates e-cigarette aerosol using a novel, positive pressure approach that utilizes clean, dry, particle-free air as the carrier gas. All parameters governing each puff profile can be adjusted, such as, operating voltage, flow rate, and puff duration.

Sample Preparation

  • Thermo Scientific Heraeus multifuge (1)
  • VWR Vortex (6) and multi-vortex mixers (4)
  • Grant-Bio PTR-35 Mixers (3)
  • Water Sonicator (2)
  • Mettler Toledo pH Meter (2)
  • Mettler Toledo ug-kg balances (4)
  • Mettler Toledo density meter(1)Beckman Coulter UV and visible spectrometer (1)
  • Labconco Rapidvap Vertex (1) and Centrivap evaporator (2)
  • Thermo Scientific and VWR dry bath (2)
  • Thermo Scientific and VWR hot plates (4)
  • Biotage Pressure+48 for SPE (1)
  • New Brunswick Scientific Excella E10 Platform Shaker (1)
  • PerkinElmer Titan MPS microwave sample preparation system (1)
  • Milli-Q Advantage A40 water purification system (1)
  • Mettler Toledo density meter(1)
  • Beckman Coulter UV and visible spectrometer (1)

Additional Resources

  • Whole-smoke exposure system (Air-liquid interface) (1)
  • Biotek EPOCH 96 well plate reader (1)
  • Bioteck ELx50 plate washer (1)
  • Thermo Scientific CO2 37°C incubator (3)
  • Life Technologies EVOS XL Cell Imaging (1)
  • Nikon compound microscope with 4-100x objectives (1)
  • Life Technologies Countess II FL cell counter (1)
  • Forma Scientific and Enviroco biosafety cabinet (2)
  • Bedfont Micro Smokerlyzer CO monitors (2)
  • CReSS Pocket puffing topography monitors (15)
  • Parameter Generation & Control DR 5000 Conditioner (1)
  • Borgwaldt LX-1 smoking machine (2)
  • Laser length measurement system (1)
  • Mettler Toledo Halogen Moisture Analyzer Model HR83-P (1)
  • Thermo Fisher -80°C Freezer (1)
  • LRP and VWR  laboratory refrigerator (4)
  • Crosley and VWR laboratory -20°C freezers (9)

Clinical and Non-Clinical Human Subject Studies

  • MicroDirect MicroLoop Spirometer (1)
  • Vyaire Medical MicroRPM  (1)
  • NIOX VERO Airway Inflammation Monitor (1)
  • Covita Micro+ Smokerlyzer® (2)
  • Welch Allyn Spot Vital Signs (1)

International Tobacco Products Repository (ITPR)

  • 250 sq. ft. -20°C walk-in storage freezer, centrally alarmed with emergency power backup
  • ITPR contains 5,854 US packs and 13,595 packs from 20 other countries

Aerosol Pollution Exposure Research Laboratory (APERL)

  • TSI Sidepak personal aerosol monitors (25)
  • Aerotrak particle counter (1)
  • TSI Q-Trak indoor air quality monitors (2)
  • SKC high-flow rate (2) and TSI low-flow rate sampling pumps (12)
  • PEM gravimetric samplers (4)
  • TSI and BIOS primary flow calibrators (4)
  • Ecochem diffusion charger (1)
  • Ecochem photoelectric charger (1)
  • Kanomax piezo balance (1)
  • Reference gases for calibration

Data processing facilities

  • Personal computer workstation equipped with GC-NPD software (1)
  • Personal computer workstation equipped with GC-MS software (1)
  • Personal computer workstation equipped with LC-MS/MS software (1)
  • Personal computer workstation equipped with GC-QTOF software (1)
  • Personal computer workstation equipped with AAS software (1)
  • Personal computer equipped with software for monitors (1)
  • Laptop equipped with software for monitors (1)
  • Personal computers equipped with statistical software for data processing (2)
  • Personal computers for lab staff (15)