Gene Targeting and Transgenic Links

  • National for Biotechnology Information (NCBI) – A national resource for molecular biology information.
  • Mouse Genome Informatics (MGI)
  • International Mouse Phenotyping Consortium (IMPC) – Incorporates the IKMC (International Knockout Mouse Consortium project (KOMP, EUCOMM).
  • Knockout Mouse Project (CSD)
  • Mouse Genome Sequence – Ensembl is a joint project between EMBL - EBI and the Wellcome Trust Sanger Institute to develop a software system which produces and maintains automatic annotation on selected eukaryotic genomes.
  • Mutant Mouse Regional Resource Center – The MMRRC distributes and cryopreserves scientifically valuable, genetically engineered mouse strains and mouse ES cell lines with potential value for the genetics and biomedical research community. They are a national network of breeding and distribution facilities plus an information coordinating center serving together as NIH's premier repository of spontaneous and induced mutant mouse and cell lines. The MMRRC is supported by the National Institutes of Health.
  • Cre-expressing database – Plan your conditional knockout.
  • RepeatMasker – Search for repeats in homologous arms.
  • International Society for Transgenic Technologies (ISTT) – Is a non-profitmaking Society, with the following aims: To foster and encourage knowledge generation, discussion, training and education, and the diffusion of the technologies and specific research used for the genetic modification of animals, in particular those aimed at generating and/or analyzing transgenic and mutant animals as particularly useful experimental models in the biology, biomedicine and biotechnology disciplines.
  • International Mouse Strain Resource (IMSR) – The IMSR is a searchable online database of mouse strains, stocks, and mutant ES cell lines available worldwide, including inbred, mutant, and genetically engineered strains. The goal of the IMSR is to assist the international scientific community in locating and obtaining mouse resources for research. Note that the data content found in the IMSR is as supplied by strain repository holders.