Dr. Paul Wallace has been Director of the RPCI’s Flow & Image Cytometry Shared Resource since 2003. He is a Member of the Pathology and Cancer Prevention and Immunology Graduate Programs, an Associate Professor in the Department of Pathology and the Department of Biotechnical and Clinical Laboratory Sciences at the University at Buffalo, Buffalo, NY. He is the President of International Society for Advancement of Cytometry (ISAC), a scientific society with over 1,700 members.
At RPCI, he directs the Department of Flow & Image Cytometry and aids investigators utilizing the facility with their experimental designs and data interpretation. He has over 30 years of experience using and developing assays to monitor immune function for which he is internationally recognized. While a Postdoctoral and later Assistant Professor at Dartmouth Medical School, he oversaw the collection of clinical correlative data for clinical trials of patients on bispecific antibody and dendritic cell based therapies. Before obtaining his PhD from the Medical College of Pennsylvania, he supervised the Esoteric Immunology Laboratory at SmithKline Clinical Labs (later Quest Laboratories) where he established the first national reference clinical flow cytometry laboratory in the U.S.
He is an Associate Editorial for Clinical Cytometry, and on the editorial boards of Current Protocols in Cytometry and Immunological Investigations. He is internationally recognized for his commitment to flow cytometric education and has been a member of ISAC’s Educational Task Force/Committee since its inception in 2006 and of the ICCS Education committee since 2003. He is a consultant with ASCP and CDC’s PETFAR (U.S. President's Emergency Plan for AIDS Relief), for which he has developed and presented training programs for the diagnosis and treatment of HIV. Since 1994 he has been on the faculty of the Bowdoin/New Mexico Annual Course in Methods and Applications of Cytometry and since 2013 a member of the Clinical Cytometry Educational Network's organizing committee.
Dr. Hans Minderman is the Associate Director of the Flow and Image Cytometry Shared Resource and a member of the Tumor Immunology and Immunotherapy Program. With over 25 years of specific experience in the field of flow and image cytometry, he is a recipient of the NIH Cancer Research Specialist award. In this role his responsibilities include managing the day-to-day operation of the Shared Resource with a specific focus on image cytometry. He consults investigators in applying ImageStream cytometry, live cell imaging, and confocal microscopy as well as conventional flow cytometry and the Luminex multiplex bead array with regards to experimental setup, methods development, data analysis and interpretation. Assisted by the technical support personnel, he also oversees development of new applications of the aforementioned technologies.
Research Laboratory Supervisor
Flow Cytometry Applications, Cell Sorting
Flow Cytometry Quality Control and Applications
Alexis Conway, PhD
Flow Cytomerty Applications Specialist
Kitty de Jong, PhD
AutoMACS, Cell Sorting, Luminex