Bioinformatics Facility Data for Grants

The Bioinformatics Resource supports the research needs of Roswell Park investigators with respect to experimental design, data integration, as well as data analysis of clinical, laboratory, and population-based studies utilizing high-throughput bioinformatics technologies. The mission is to advance cancer research and cancer treatment by providing an array of bioinformatics shared research and services to the institute community through collaboration. A key expertise is to develop and utilize state of art bioinformatics algorithms to design, analyze and integrate various voluminous “-omics” data for a better understanding of the molecular mechanisms underlying human cancer initiation, progression and prognosis.

The Bioinformatics Resource takes advantage of several major computing resources available. First, each staff has a Dell Linux workstation, which is ideal for moderately compute-intensive bioinformatics projects. Second, through collaboration with the Roswell Park IT department, the resource has a high-performance computing cluster with 1,600 processors suitable for whole-genome sequencing analysis. Third, through collaboration with the Center for Computational Research at University at Buffalo, resource staff has high-priority access to the Linux cluster with more than 2,000 processors. These high-performance computing cluster resources are specifically designed for largely compute-intensive bioinformatics projects.

The Bioinformatics Resource will develop novel and effective bioinformatics tools for research and clinical applications, assist researchers to perform high-throughput “-omic” experiments guided by computational insights, ensure that the correct bioinformatics design and analysis methodologies are employed in relevant Roswell Park grant and manuscript preparations.