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Atomic Absorption
TomTec

Bioanalytics, Metabolomics & Pharmacokinetics (BMPK) Equipment

BMPK Instrumentation

  • Applied Biosystems 5500 QTrap triple quadrupole (ESI/APCI-LC/MS/MS)
  • Applied Biosystems 5500 triple quadrupole (ESI/APCI-LC/MS/MS)
  • Thermo Scientific TSQ Vantage triple quadrupole (ESI/APCI-LC/MS/MS)
  • Applied Biosystems API3000 triple quadrupole (ESI LC/MS/MS)
  • Waters Ultra Performance Liquid Chromatography (UPLC) system with  fluorescence and UV detection
  • Waters BioAlliance High Performance Liquid Chromatography (HPLC) system with  fluorescence and UV detection
  • Abbott i1000SR Architect chemiluminescent magnetic microparticle immunoassay (CMIA)
  • Perkin Elmer Analyst 600 graphite furnace atomic absorption
  • Biotek Synergy 96-well plate reader providing fluorescence and UV detection
  • Tomtec Quadra 4 robotic handling system

BMPK Modeling Software

  • Phoenix WinNonlin Professional: Non-compartmental and compartmental modeling
  • ADAPT 5 and S ADAPT: individual compartmental PK and PK/PD modeling
  • NONMEN: nonlinear mixed effect modeling software for population analysis to determine sources of variability in the PK and PD of a drug
  • WinPOPT: provides information for PK and /or PK/PS sampling strategies
  • SAS 9.3: used to manage and clean databases, and create graphics and tables