Vinorelbine

Brand Names

Navelbine®, vinorelbine tartrate. (There may be other names for this medication.)

How is Vinorelbine Administered?

Your medicine will be given by injection into a vein.

What Is It Used For?

This drug is used to treat some types of lung cancer.

How Does it Work?

Cancer is a group of diseases in which abnormal cells divide without control. Both normal and cancer cells go through cycles that include a resting phase, active growing phases, and division. Your chemotherapy schedule is based upon the type of cancer you have, the rate at which they divide, and the times when each drug is the most likely to be effective. This is why chemotherapy is typically given in cycles.

Vinorelbine is a type of plant alkaloid called a vinca alkaloid. It attacks the cancer cells during specific stages of the cell cycle. If the cells are unable to divide, they die. The faster cells are dividing (reproducing), the more likely it is that chemotherapy will damage/kill the cells. Unfortunately, chemotherapy does not know the difference between cancer cells and normal cells that reproduce frequently. The cells in your body that are the most likely to be affected by chemotherapy are the cells that line the digestive tract (mouth, stomach, intestines), hair follicles, and blood cells.

These normal cells will eventually grow back and be healthy. During treatment, however, you may experience side effects from the chemotherapy’s effects on these normally fast reproducing cells including nausea, vomiting, diarrhea, mouth sores, hair loss, and decreased blood counts. Low blood counts may cause fatigue, anemia, and a significant decrease in your ability to fight off infections.

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