Zanosar (There may be other brand names for this medication)
How is It Administered?
The drug is given by injection into a vein (intravenous or IV).
What Is This Drug Used For?
Streptozocin is used to treat pancreatic cancer, carcinoid tumors, Hodgkin's disease, colorectal cancer, hepatoma, malignant melanoma, pheochromocytoma, epidermoid carcinoma of the lung, some types of lymphoma and leukemia, and metastatic sarcomas.
How Does Streptozocin Work?
Cancer is a group of diseases in which abnormal cells divide without control. Both normal and cancer cells go through cycles that include a resting phase, active growing phases, and division. Your chemotherapy schedule is based upon the type of cancer you have, the rate at which they divide, and the times when each drug is the most likely to be effective. This is why chemotherapy is typically given in cycles.
Streptozocin is in a class of drugs known as alkalyting agents; specifically a nitrosurea drug. Alkylating agents affect cells while they are in their “resting phase”. Nitrosurea drugs have the rather unique ability to cross the blood-brain barrier.