Pegfilgrastim

Brand Names

NeulastaTM (There may be other brand names for this medication)

How is it Administered?

This medicine is given as a shot under your skin, usually one injection during each of your chemotherapy treatment cycles.

What is it Used For?

This drug is a granulocyte colony-stimulating factor (G-CSF), it helps white blood cells grow and mature. (White blood cells help your body fight infection.) It is used to treat or prevent infections caused by chemotherapy. Pegfilgrastim is a long-acting version of the drug filgrastim.

How Does it Work?

Pegfilgrastim is a type of biologic response modifier, specifically a granulocyte colony- stimulating factor or G-CSF.

Blood cells are produced in the bone marrow, the spongy center inside many of your bones. White blood cells (WBCs), red blood cells (RBCs), and platelets are made and then travel through your body to fight infection (WBCs), carry oxygen & remove waste products (RBCs), and help blood to clot (platelets).

Side effects of radiation and many chemotherapy drugs can damage your bone marrow (temporarily) and decrease production of these blood cells. People receiving some cancer therapies can therefore be more susceptible to infection, fatigue, and bleeding problems.

G-CSFs are made to stimulate your bone marrow to produce more neutrophils, a type of white blood cells, and help reduce your risk for infection.

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