Panitumumab

Brand Names

Vectibix® (There may be other names for this medication.)

How is Panitumumab Administered?

Panitumumab is given by infusion into a vein (intravenous or IV), usually every 2 weeks.

Why am I Receiving Panitumumab?

This drug treats colon or rectal cancer that expresses EGFR (see “How it Works”) and that has spread during or after treatment with certain chemotherapy medications (oxaliplatin, fluoropyrimidine, or irinotecan). Panitumumab may be prescribed for other uses.

How Does it Work?

Cancer is a group of diseases in which abnormal cells reproduce uncontrollably. Traditional chemotherapy drugs identify and attack cancer cells because of their rapid reproduction. They also attack normal cells that reproduce quickly like those in the bone marrow and digestive tract.

Panitumumab is a type of targeted therapy, and it is designed to work differently. It is in a class of medications called monoclonal antibodies, and this is how it works. It attaches to a protein (EGFR or Epidermal Growth Factor Receptor) on the surface of the cancer cells and blocks the growth factor. This interferes with the cells’ ability to grow and reproduce. Some normal cells have EGFR on their surface, and these cells may be affected as well.

Continue Reading Detailed Drug Profile