Brand Names

Zofran® (There may be other brand names for this medication)

How is Ondansetron Administered?

Your medicine may be given by subcutaneous injection (just under the skin), usually in the abdomen. Ondansetron also comes as a tablet, a rapidly dissolving tablet, and an oral solution to take by mouth.

What Is It Used For?

This drug is given to prevent nausea and vomiting caused by chemotherapy or radiation therapy.

How Does it Work?

Ondansetron is in a class of medications called 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.

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