Mitoxantrone

Brand Names

Novantrone® (There may be other brand names for this medication).

How is it Administered?

MItoxantrone is given as an injection into a vein (intravenous or IV).

What is it Used For?

Mitoxantrone is used with steroid medications for men with advanced prostate cancer who did not respond to hormone therapy. It is also used to treat leukemia (AML), breast cancer, and non-Hodgkin lymphoma.

How Does it Work?

Cancer is a group of diseases in which abnormal cells divide without control. Both normal and cancer cells go through cycles that include a resting phase, active growing phases, and division. Your chemotherapy schedule is based upon the type of cancer you have, the rate at which they divide, and the times when each drug is the most likely to be effective. This is why chemotherapy is typically given in cycles.

The faster cells are dividing (reproducing), the more likely it is that chemotherapy will damage/kill the cells. Unfortunately, chemotherapy does not know the difference between cancer cells and normal cells that reproduce frequently. The cells in your body that are the most likely to be affected by chemotherapy are the cells that line the digestive tract (mouth, stomach, intestines), hair follicles, and blood cells. These normal cells will eventually grow back and be healthy. During treatment, however, you may experience side effects from the chemotherapy’s effects cells.

Mitoxantrone is an antitumor antibiotic, in a class of drugs called anthracenediones. It acts upon and interferes with the cells during certain phases of the cells’ reproductive cycle and slows or stops the growth of the cancer.

Continue Reading Detailed Drug Profile