Mitoxantrone

Brand Names

Novantrone® (There may be other names for this medication.)

How is it Administered?

Your medication will be given by injection into a vein (intravenous or IV), usually in your arm, wrist, hand or chest.

Why am I Taking Mitoxantrone?

Mitoxantrone is used with steroid medications for men with advanced prostate cancer who did not respond to hormone therapy. It is also used to treat leukemia (AML), breast cancer, and non-Hodgkin lymphoma.

How Does it Work?

Cancers are diseases in which abnormal cells reproduce uncontrollably. Your chemo schedule is based upon:

  • your cancer type and how fast the cancer cells reproduce
  • the phase of the cell cycle when the chemo is most effective — the resting, growing, or reproduction phases

With these factors in mind, your doctors create a chemo schedule to give each medication when it will do the most damage to the cancer cells.

Mitoxantrone is an antitumor antibiotic, in a class of drugs called anthracenediones. It interferes with the cancer cells’ reproduction and slows or stops the growth of the cancer.

Many chemo medications identify and attack cancer cells because they reproduce quickly. Some cells in your body normally reproduce quickly and they are likely to be damaged/destroyed by chemo. These normal cells will eventually grow back and be healthy. During treatment, however, you may experience side effects from chemo’s effects on these cells.

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