Brand Names

Wellcovorin , folinic acid, citrovorum factor (There may be other brand names for this medication)

How is it Administered?

This medication comes as a tablet to be taken by mouth, or it can be given as a injection

What is Leucovorin Used For?

Leucovorin may be used to enhance the effects of the chemotherapy medication 5-FU or to reduce the side effects of is methotrexate.

How Does Leucovorin Work?

Leucovorin is in a class of medications called folic acid (vitamin B12) analogs. It works by protecting healthy cells from the effects of some drugs, such as methotrexate or, in the case of 5 FU, to allow the chemotherapy drug to remain in the cells longer, in the hopes of allowing the 5-FU to exert more of its anticancer effects.

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