Neupogen®, G-CSF/granulocyte-colony stimulating factor (There may be other brand names for this medication.)
How is Filgrastim Given?
This medication is given by injection under the skin (subcutaneously) or infusion into a vein (intravenous or IV). Usually, it is given once a day.
Why am I Receiving Filgrastim?
Filgrastim does not treat cancer; it is used to decrease the chance of infection in people who:
- are receiving chemotherapy that causes neutropenia — a condition in which there are a low number of neutrophils in the blood. Neutrophils are a type of white blood cell that fights infection.
- are undergoing bone marrow transplants
- have chronic neutropenia
- will have leukapheresis (a treatment that removes blood to collect a specific type of blood cell, and then returns the rest of the blood to the body)
How Does it Work?
Filgrastim is a granulocyte colony-stimulating factor (G-CSF), a type of biologic response modifier. Granulocytes are a type of white blood cell that is made of small granules. Neutrophils are one type of granulocyte.
Blood cells begin in the bone marrow, the spongy center inside many of your bones. Chemotherapy and radiation treatments can damage your bone marrow and temporarily decrease the production of blood cells. A decrease in white blood cells can make you more susceptible to infection. Filgrastim stimulates your bone marrow to produce more white blood cells and help reduce your risk of infection.