Infliximab

Brand Names

Remicade® (There may be other brand names for this medication)

How is it Administered?

Your medicine will be given slowly by infusion into a vein (intravenous or IV). Usually, it takes about 2 hours to get one dose.

What is it Used For?

This drug is a monoclonal antibody used to manage transplant rejection, and to relieve symptoms of certain autoimmune disorders such Crohn’s Disease and rheumatoid arthritis.

How Does it Work?

Infliximab is a tumor necrosis factor (TNF) inhibitor. It works by blocking your body’s normal immune/inflammatory response. Normally, when your body detects the presence of a foreign substance, it mounts a defense to isolate or kill the invader. We may experience these attacks as a fever, or local swelling, redness, and pain. When a person has an autoimmune disease, there is no invader, the body, for unknown reasons, attacks itself.

If you have had a transplant, you do not want your body to attack the new tissue and possibly cause your body to reject the transplant. Using medications like infliximab helps prevent transplant rejection, but it also makes you more vulnerable to infections.

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