Other Names

DTIC-Dome®, DTIC, DIC, imidazole carboxamide (There may be other brand names for this medication.)

How is it Administered?

Your medicine will be given by injection or infusion into a vein (intravenous or IV), usually in your arm, wrist, hand or chest.

Why am I Receiving Dacarbazine?

This drug is used to treat melanoma, Hodgkin’s disease, soft tissue sarcomas, neuroblastoma, rhabdomyosarcoma, medullary carcinoma of the thyroid cancer, and islet cell carcinoma (pancreatic cancer).

How Does it Work?

Cancer is a group of diseases in which abnormal cells divide without control. Both normal and cancer cells go through cycles that include a resting phase, active growing phases, and division (when the cells reproduce/multiply). Your chemotherapy schedule is based upon the type of cancer you have, the rate at which the cancer cells divide, and the times when each drug is the most likely to be effective. This is why chemotherapy is typically given in cycles.

Dacarbazine is in a class of drugs known as alkylating agents. Alkylating agents are most active in the resting phase of the cell cycle. You may hear it called a cell-cycle non-specific drug.

Continue Reading Detailed Drug Profile