Busulfan

Other Names

Busulfex®, Myleran® (There may be other names for this medication.)

How is it Given?

Busulfan can be taken by mouth in tablet form or it can be infused into a vein (intravenous or IV). Take the tablet(s) around the same time every day. Do not take more or less than prescribed.

Why am I Taking Busulfan?

This drug is used to treat chronic myelogenous leukemia (CML), certain blood disorders such as polycythemia vera, and to prepare the body for stem cell/bone marrow transplants.

How Does it Work?

Cancer is a group of diseases in which abnormal cells reproduce uncontrollably. Your chemo schedule is based upon the type of cancer you have, how fast the cancer cells reproduce, and the times when each drug is the most likely to be effective. This is why we typically give chemotherapy in cycles.

Busulfan is in a class of drugs known as alkylating agents. It attacks cells in the resting phase of the cell cycle. The cell cycle includes resting, active growing, and division (reproduction) phases.

Traditional chemotherapy agents identify and attack cancer cells by how quickly they reproduce. Unfortunately, normal cells that reproduce quickly are also affected, which can result in side effects. These normal cells will eventually grow back and be healthy.

Continue Reading Detailed Drug Profile