Brand Names

Stivarga® (There may be other names for this medication.)

How is Regorafenib Administered?

Regorafenib is a tablet, and it must be swallowed whole. Usually, you take it once a day for 21 days, followed by a week off. Take it at the same time every day along with a low fat breakfast. The low fat breakfast should have less than 30% of its calories from fat.

Why Am I Taking Regorafenib?

Regorafenib treats colon or rectal cancer that has spread (metastasized) to other parts of the body for people who have already been treated with certain chemotherapy agents.

How Does it Work?

Regorafenib is a type of targeted therapy, rather than traditional chemotherapy. Specifically, it is a kinase inhibitor.

Cancer is a group of diseases in which abnormal cells divide without control. Traditional chemo medications identify cancer cells by their rapid rate of reproduction – and then attack those cells.

Regorafenib works differently. Instead of attacking any rapidly reproducing cells, it blocks the actions of some of the kinase proteins. These proteins would normally help the tumor to grow and build new blood vessels to feed itself. Blocking these kinase proteins may help stop the growth of tumors.

Continue Reading Detailed Drug Profile