Megestrol Acetate

Brand Names

Megace® (There may be other brand names for this medication)

How is it Administered?

Your medicine will be taken by mouth as a tablet or a liquid.

What is it Used For?

This drug is used to treat cancer of the breast or endometrium (uterus). Also used to increase appetite and prevent weight loss.

How Does it Work?

Our bodies produce hormones that travel through the bloodstream and have effects on “target” organs and tissues throughout our bodies. Hormones play a vital role in our metabolism, out sexual characteristics, fluid balance, growth, and many other important functions.

Sometimes, certain cancers grow in response to the presence of a particular hormone, so drugs/hormones have been developed either to stop the production of that hormone or to block the hormone from attaching to receptors on our cells. In doing so, it effectively blocks the effects of that hormone.

Megestrol is a type of hormone therapy, specifically a progestin (a synthetic version of the hormone progesterone.) Megestrol interferes with the effects of estrogen on certain cancers that are encouraged to grow in the presence of estrogen.

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