Fluorouracil Topical, 5-FU

Brand Names

Carac® cream, Efudex® cream, Efudex® solution, Fluoroplex® cream (There may be other names for this medication.)

How is Fluorouracil Administered?

Fluorouracil comes as a solution and a cream to apply to the skin. Usually, it is applied to the affected areas twice a day. To help you remember to use fluorouracil, apply it around the same times every day.

Why am I Using Fluorouracil?

Fluorouracil cream and solution are used to treat actinic keratosis, thick, rough, scaly spot(s) on your skin in areas that have been exposed to sunlight for many years. Actinic Keratosis is not skin cancer, but if left untreated, a small percentage will become squamous cell skin cancer. The medication is sometimes used to treat superficial basal cell skin cancer.

How Does it Work?

Fluorouracil is in a class of medications called antimetabolites. It works by killing fast-growing cells such as the abnormal cells in actinic keratosis and basal cell carcinoma.

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