Other Names

Fludara®, FAMP (There may be other names for this medication.)

How is it Given?

Fludarabine is given by infusion into a vein (IV or intravenous), usually over 30 minutes. Typically, the infusions are given once a day for 5 days in a row, for each chemotherapy cycle.

Why am I Receiving Fludarabine?

This drug treats chronic lymphocytic leukemia (CLL) and non-Hodgkin’s lymphoma.

How Does it Work?

Cancer is a group of diseases in which abnormal cells reproduce uncontrollably. Your chemo schedule is based upon the type of cancer you have, how fast the cancer cells reproduce, and the times when each drug is the most likely to be effective. This is why we typically give chemotherapy in cycles.

Fludarabine is in a class of drugs known as antimetabolites. It attacks cells at very specific phases in the cell cycle. The cell cycle includes resting, active growing, and division (reproduction) phases. Once fludarabine is inside you, your body changes it so it is able to enter cells. Once inside the cells, it interferes with their ability to reproduce.

Traditional chemotherapy agents identify and attack cancer cells by how quickly they reproduce. Unfortunately, normal cells that reproduce quickly are also affected, which can result in side effects. These normal cells will eventually grow back and be healthy.

Continue Reading Detailed Drug Profile