Brand Names

Kryprolis® (There may be other names for this medication.)

How is Carfilzomib Administered?

Your medication will be given by infusion (injection) into a vein (intravenous, IV), usually in your arm, wrist, hand, or chest. Typically, it is given for 2 days in a row for 3 weeks, followed by a break for 12-14 days. IV fluids are normally given with this medication.

Why Am I taking Carfilzomib?

Carfilzomib is used to treat people who have multiple myeloma that has progressed after being treated with bortezomib and another therapy. There are studies to see if it can be used to treat other cancers.

How Does it Work?

Carfilzomib is a type of targeted therapy, rather than traditional chemotherapy. Specifically, it is a proteasome inhibitor.

Cancer is a group of diseases in which abnormal cells divide without control. Traditional chemo medications identify cancer cells by their rapid rate of reproduction – and then attack those cells. Unfortunately, there are normal cells in our bodies that reproduce rapidly too, and these cells can be affected, which can result in unpleasant side effects.

Carfilzomib is designed to work differently. Instead of attacking all rapidly reproducing cells, it blocks the action of an abnormal protein that triggers cancer cells to reproduce. Blocking their ability to reproduce leads to the cells’ death.

Continue Reading Detailed Drug Profile