Marc Ernstoff, MD

Professor and Chair, Department of Medicine
Senior Vice President for Clinical Investigation
The Katherine Anne Gioia Chair of Medicine
Roswell Park Comprehensive Cancer Center
Section Chief, Hematology/Oncology
Professor of Medicine
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo

Make an appointment online or call us at 1-800-Roswell Request an Appointment

Areas of Expertise: 
Kidney cancer
Melanoma

Biography

Over the past 30 years, I have focused my clinical research in expanding our understanding of the immunobiology of human cancer and the development of new immune therapies. Our NCI funded clinical trials were aimed at minimizing regulatory and suppressive pathways and enhancing existent tumor-specific immune function.

I did my cancer immunology and immunotherapy training with John M. Kirkwood while at Yale University. I continued to develop my experience and qualifications as a translational immunotherapy clinical scientist while at Yale and the University of Pittsburgh and Pittsburgh Cancer Institute. I was a cadre member of the both CALGB and ECOG melanoma programs and am currently a member of the Alliance Experimental Therapeutics Program.

I am currently the Geisel PI on the Cancer Immunotherapy Trial Network and on the executive council of the Cytokine Working Group. I have published over 200 original research manuscripts in the areas of renal cell cancer, melanoma and immune therapy strategies including cytokine therapies, dendritic cell vaccines, immune checkpoint inhibition, targeted therapies and ex vivo expanded effector cells for adoptive transfer. My laboratory has developed phenotypic, functional and molecular assays which enable us to explore the immune response to disease and therapy. While at the University of Pittsburgh and the Pittsburgh Cancer Institute, I was the Director of the Hematology/Oncology Fellowship Program and PI on a T32 Training award from the NCI. 

Over the years, I have successfully mentored five medical students, ten residents, 39 postdoctoral/fellows, and 18 junior faculty. I was Staff Physician at the Taussig Cancer Institute, Cleveland Clinic Foundation and Director of the Melanoma Program and Professor in the Cleveland Clinic Lerner School of Medicine. In 2016, I assumed the role of Professor and Chair, Department of Medicine, Senior Vice President for Clinical Investigation, The Katherine Anne Gioia Chair of Medicine, Roswell Park Cancer Institute and Professor and Chief of the Section of Oncology at the University of Buffalo.

Background

Education and Training: 
1978 – MD – New York University School of Medicine, New York, NY
Residency: 
1981 – Internal Medicine – Bronx Municipal Medical Center and The Hospital of The Albert Einstein College of Medicine, New York, NY
Fellowship: 
1984 – Medical Oncology – Yale University School of Medicine, New Haven, CT
Board Certification: 
1989 - Diplomate, Subspecialty of Medical Oncology
1981 - Diplomate, American Board of Internal Medicine
1979 – Diplomate, National Board of Medical Examiners
Professional Memberships: 
2000-present - American Society of Clinical Oncology Program Committee
1998-present - International Cytokine Society
2016-present - National Comprehensive Cancer Network
1997-2005 - Member, WHO Melanoma Programme
1997-present - American Society of Clinical Oncology, Melanoma Program Committee
1988-present - Society for Biological Therapy/Society of Immunotherapy of Cancer
1988-present - Clinical Immunology Society
1983-present - International Society of Interferon Research
1983-present - American Society of Clinical Oncology
1983-present - American Association for Cancer Research
Honors and Awards: 
2017-2018 - Marquis Who’s Who in America for Excellence in Medicine
2012 - Best educator, Hematology/Oncology Fellowship Program Geisel School of Medicine
2012 - O. Ross McIntyre Professor of Medicine
2011 - Team Science Award Society of Immunotherapy of Cancer
2009-present - New Hampshire Magazine Top Doctors Poll
2008-2009 - Who’s Who Among Executives and Professionals, “Honors Edition”
2005-2006 - The United Who’s Who Registry, “Honors Edition”
2005-2006 - Who’s Who in American Education, 7th edition
2000-2014 - distinguished teacher awards for Residency Training, Department of Medicine, Hitchcock Clinic
2012 - Best educator, Hematology/Oncology Fellowship Program Geisel School of Medicine
2012 - O. Ross McIntyre Professor of Medicine
2011 - Team Science Award Society of Immunotherapy of Cancer Society of Immunotherapy for Cancer
2009-present New Hampshire Magazine Top Doctors Poll
2004-2005 - Who’s Who in Science and Engineering, 7th edition
2003-2004 - Who’s Who in Medicine and Healthcare, 4th edition
2004-present - Faculty of 1000 Medicine
1997 - First Steven B. Currier Clinical Oncology Scholar, endowment to support clinical melanoma research
1996-present - The Best Doctors in America
1975 - Bernard Baruch Award, American College of Rehabilitation and Physical Medicine