Dr. Lili Tian

Lili Tian

PhD

Special Interests:

Statistical methods in diagnostic studies Generalized inference Empirical likelihood approach Statistical methods with genomic data Design of clinical trials Goodness-of-fit testing Order-restricted inference Longitudinal data analysis Analysis of medical expenditure data General statistical inference Cancer research Epidemiology studies

About Me

Biography:

Dr. Lili Tian earned her MA (1999) and PhD (2001) in Statistics from the University of Rochester, as well as a MA in Physics (1997). She earned her BS and MS in Physics from Shandong University in China.

Dr. Tian joined the Department of Biostatistics and Bioinformatics at Roswell Park Comprehensive Cancer Center (Roswell Park) as a Consultant in 2005 and became an Associate Professor of Oncology in 2007. She was an Associate Professor 2005-2013, and has been full Professor since Sept. 2013 in the department of Biostatistics at SUNY at Buffalo.


Credentials

Positions

Roswell Park Comprehensive Cancer Center
  • Professor of Biostatistics and Oncology
  • Department of Biostatistics and Bioinformatics
State University of New York at Buffalo
  • Professor, Biostatistics

Background

Education and Training:

  • PhD - Statistics, University of Rochester, Rochester, NY
  • MA - Statistics, University of Rochester, Rochester, NY
  • MA - Physics, University of Rochester, Rochester, NY
  • MA - Physics, Shandong University, China
  • BS - Physics, Shandong University, China

Publications

Chadha MK, Tian L, Mashtare T, Payne V, Silliman C, Levine E, Wong M, Johnson C, Trump DL. Phase 2 trial of weekly intravenous 1,25 dihydroxy cholecalciferol (calcitriol) in combination with dexamethasone for castration-resistant prostate cancer. Cancer 2010; 116(9):2132-2139

Tian L. Confidence interval estimation of partial area under curve based on combined biomarkers. Computational Statistics and Data Analysis 2010; 54(2):466-472

Yu J, Vexler A, Tian L. Analyzing incomplete data subject to a threshold using empirical likelihood methods: an application to a pneumonia risk study in an ICU setting. Biometrics 2010; 66(1):123-130

Kang L, Vexler A, Tian L, Cooney M, Buck Louis GM. Empirical and parametric likelihood interval estimation for populations with many zero values: Application for assessing environmental chemical concentrations and reproductive health. Epidemiology (Cambridge, Mass.) 2010; 21(Suppl. 4):S58-S63

Muindi JR, Adjei AA, Wu ZR, Tian L, Sucheston LE, Johnson CS, Trump DL, Fakih MG. A comprehensive characterization of cholecalciferol supplementation induced changes in the vitamin D-3 metabolic pathway in metastatic colorectal cancer patients. Proceedings of the American Association for Cancer Research Annual Meeting 2010; 51:21

Tian L, Xiong C, Lai C-Y, Vexler A. Exact confidence interval estimation for the difference in diagnostic accuracy with three ordinal diagnostic groups. Journal of Statistical Planning and Inference 2011; 141(1):549-558

Vexler A, Yu J, Tian L, Liu S. Two-sample nonparametric likelihood inference based on incomplete data with an application to a pneumonia study. Biometrical Journal 2010; 52(3):348-361

Lal D , Fetterly GJ , Wetzler M , Prey J , Murphy M , Mashtare TJ , Tian L , Lin M-H , Perez AM , Marinaro J , Demock K , Park JA , Wang ES. Aflibercept exerts antivascular effects and enhances levels of anthracycline chemotherapy in vivo in human acute myeloid leukemia models. Molecular Cancer Therapeutics 2010; 9(10):2737-2751

Chadha MK, Fakih M, Muindi J, Tian L, Mashtare T, Johnson CS, Trump D.Effect of 25-hydroxyvitamin D status on serological response to influenza vaccine in prostate cancer patients. Prostate 2011; 71(4):368-372

Fakih MG, Trump DL, Johnson CS, Tian L, Muindi J, Sunga AY.Chemotherapy is linked to severe vitamin D deficiency in patients with colorectal cancer. International journal of colorectal disease 2009; 24(2):219-224

Trump DL, Tan W, Tian L, Nesline MK, Hollis BW, Silliman CG, Ashraf U, Fakih MG, Sunga AY, Chadha MK, Johnson CS. Vitamin D deficiency and insufficiency among patients with prostate cancer. BJU International 2009; 104(7):909-914

Vexler A, Shan G, Kim S, Tsai W-M, Tian L, Hutson AD. An empirical likelihood ratio based goodness-of-fit test for Inverse Gaussian distributions. Journal of Statistical Planning and Inference 2011; 141(6):2128-2140

Chadha MK, Ashraf U, Lawrence D, Tian L, Levine E, Silliman C, Escott P, Payne V, Trump DL. Phase II study of fulvestrant (Faslodex) in castration resistant prostate cancer. Prostate 2008; 68(13):1461-1466

Deeb KK, Johnson CS, Morrison CD, Tangrea MA, Tian L, Bshara W, Omilian AR, Karpf AR, Luo W, Trump DL. Differential vitamin D 24-hydroxylase/CYP24A1 gene promoter methylation in endothelium from benign and malignant human prostate. Epigenetics 2011; 6(8):994-1000

AL-Hussaini MH, Johnson CS, Muindi J, Chadha MK, Silliman C, Tian L, Tan W, Nesline M, Sandecki A, Kuettel MR, Mohler J, Guru K, Trump DL. Serum 25(OH) vitamin D3 response to vitamin D3 supplementation in men with prostate cancer: Results of a randomized phase II trial : ASCO Meeting Abstracts Part 1. Journal of Clinical Oncology 2011; 29(15 Suppl.):e13060

Chadha MK, Fakih MG, Tian L, Mashtare T, Nesline M, Davis W, Silliman C, Trump DL. Effect of 25 hydroxy vitamin D status on serological response to influenza vaccine in cancer patients. Journal of Clinical Oncology 2009; 27(15 Suppl.):Abstract #e20575

Demock KM, Marinaro J, McInnis I, Ford LA, Wetzler M, Tian L, Deeb G, Wang ES. Hypoxia-Inducible Factor-1 Alpha (HIF-1 alpha) and HIF-2 alpha Are Independent Prognostic Factors for Normal Karyotype Acute Myeloid Leukemia (NK AML). Blood 2008; 112(11):887

Demock KM, Marinaro J, Sobczyk A, Ford LA, Wetzler M, Deeb G, Tian L, Wang ES. Expression of Vascular Endothelial Growth Factor Receptors VEGFR-1 and VEGFR-2 Are Prognostic Factors in Normal Karyotype Acute Myeloid Leukemia (NK-AML). Blood 2008; 112(11):886-887

Muindi JR, Adjei AA, Panasiewicz MA, Wu ZR, Tian L, Sucheston LE, Johnson CS, Trump DL, Fakih MG. Profiling serum vitamin D-3 metabolites in colorectal cancer patients on cholecalciferol supplementation.: Correlation with single nucleotide polymorphisms (SNPs) in the major vitamin D-3 metabolizing genes.Proceedings of the American Association for Cancer Research Annual Meeting 2009; 50:827

Wang ES, Sobczyk A, Marinaro JM, Wetzler M, Tian L, Deeb G. VEGF-A, VEGF-C, and CD31 expression by leukemia cells are prognostic factors for overall survival in acute myeloid leukemia (AML). Blood 2007; 110(11 Part 1):Abstract #2392

Dong T, Tian L, Hutson A, Xiong C. Parametric and non-parametric confidence intervals of the probability of identifying early disease stage given sensitivity to full disease and specificity with three ordinal diagnostic groups. Statistics in medicine 2011; 30(30):3532-3545

Cai T, Tian L, Uno H, Solomon SD, Wei LJ. Calibrating parametric subject-specific risk estimation. Biometrika 2010; 97(2):389-404

Gilder K, Ting N, Tian L, Cappelleri JC, Choudary Hanumara R. Confidence intervals on intraclass correlation coefficients in a balanced two-factor random design. Journal of Statistical Planning and Inference 2007; 137(4):1199-1212

Krishnamoorthy K, Tian L. Inferences on the difference and ratio of the means of two inverse Gaussian distributions. Journal of Statistical Planning and Inference 2008; 138(7):2082-2089

Ma C-X, Tian L. A parametric bootstrap approach for testing equality of inverse gaussian means under heterogeneity. Communications in Statistics: Simulation and Computation 2009; 38(6):1153-1160

Tian L. Inferences on standardized mean difference: the generalized variable approach. Statistics in Medicine 2007; 26(5):945-953

Tian L. Confidence intervals for P(Y1>Y2) with normal outcomes in linear models. Statistics in Medicine 2008; 27(21):4221-4237

Tian L. Generalized inferences on the overall treatment effect in meta-analysis with normally distributed outcomes. Biometrical Journal 2008; 50(2):237-247

Tian L. Inferences about the between-study variance in meta-analysis with normally distributed outcomes. Biometrical Journal 2008; 50(2):248-256

Tian L, Mudholkar GS. Testing equality of order constrained inverse Gaussian means. Communications in statistics: Theory and Methods 2007; 36(5):897-906

Tian L, Vexler A, Yan L, Schisterman EF. Confidence interval estimation of the difference between paired AUCs based on combined biomarkers. Journal of Statistical Planning and Inference 2009; 139(10):3725-3732

Tian L, Wilding GE. Confidence interval estimation of a common correlation coefficient. Computational Statistics and Data Analysis 2008; 52(10):4872-4877

Tian L, Wu J. Inferences on the mean response in a log-regression model: the generalized variable approach. Statistics in Medicine 2007; 26(28):5180-5188

Tian L, Wu J. Inferences on the common mean of several log-normal populations: the generalized variable approach. Biometrical Journal 2007; 49(6):944-951

Lai C-Y, Tian L, Schisterman EF. Exact confidence interval estimation for the Youden index and its corresponding optimal cut-point. Computational Statistics and Data Analysis 2012; 56(5):1103-1114

Li X, Tian L, Wang J, Muindi JR. Comparison of quantiles for several normal populations. Computational Statistics and Data Analysis 2012; 56(6):2129-2138

Augoff K, Zhang L, Rivera L, Khoury T, Tian L, Groman A, Watroba N, Plow EF, Kulkarni S, Sossey-Alaoui K. Increased expression levels of WAVE3 are associated with breast cancer progression and metastasis. Proceedings of the American Association for Cancer Research Annual Meeting 2011; 52:Abstract #3206

Haller AC, Morrison C, Payne-Ondracek R, Tan W, Tian L, Mohler J, Li F.Prostate derived Ets (E-twenty six) transcription factor (PDEF) as a prognostic biomarker for metastatic prostate cancer. Proceedings of the American Association for Cancer Research Annual Meeting 2011; 52:Abstract #4173

Kulkarni S, Augoff K, Rivera L, McCue B, Khoury T, Groman A, Zhang L, Tian L, Sossey-Alaoui K. Increased expression levels of WAVE3 are associated with the progression and metastasis of Triple Negative Breast Cancer. PloS One 2012; 7(8):e42895

Tian LL, Li XM, Yan L. Testing equality of generalized treatment effects.Journal of Biopharmaceutical Statistics 2012; 22(3):582-595