Exploring Genetic Pathways to Slow Down Aging and Reduce the Risk of Age-Related Cancers
Aging is a complex disease associated with many pathological conditions, including cancer. Marina Antoch, PhD, is leading research funded by donations that is exploring how certain genetic pathways can be manipulated to slow down the aging process.
Dr. Antoch’s previous research indicate that aging can be slowed down by an immunosuppressor drug known as rapamycin, a tumor suppressor called p53 and BMAL1 protein, a component of the molecular clock, all targeting same genetic pathway. The goal of Dr. Antoch’s latest research is to understand how these pathways integrate, with the long-term goal of using this information to develop effective therapies that decelerate aging and age-related diseases.