Trends in Tumor Immunology

Course ID: 
MIR 509

General Class Notes:

This course requires, as a pre-requisite, an upper level General Immunology course. If you do not have a strong background in Immunology, you will have difficulty with the material covered.


This is a 2 credit hour course. The first part of the course will be composed of 9 lectures and required reading assigned by faculty on specific advanced topics in tumor immunology. This section is followed by an in-class, essay/short-answer exam worth 50% of your grade.

The second part of the course will be composed of individual student oral presentations (via PowerPoint; approximately 30 minutes each) that summarize detailed, well-organized information from a recent review article in Tumor Immunology. The review articles will be provided to all students to choose from on the first day of class. This presentation is worth 40% of your grade.

This course will also include a discussion of Medical Ethics and aspects of professional and responsible career development. Further, there will be time devoted to topics in professional career development in research within many classes. Participation in this section of the class is worth 10% of your grade.

Attendance Policy

Classes are held Wednesdays from 3-5 PM in CGP L5-130. Students are expected to attend all classes and participate with discussion and questions. Students are expected to be on time for each lecture. Unexcused absence from class will result in a 10% reduction in overall grade for each class missed. There will be no make-up exams unless there is a confirmed illness (students must have an excuse from a local doctor).

Questions or Concerns

Students are advised to discuss any questions or concerns that may arise during the course with the Course Coordinators, Jason Muhitch and Michelle Messmer, who will be overseeing attendance and student participation.


Course Coordinators:

Drs. Jason Muhitch & Michelle Messmer

Jason Muhitch, Ph.D.
Department of Urology
Phone: (716)845-7180
CGP Rm L5-143

Michelle Messmer, Ph.D.
Department of Immunology
Phone: (716)845-3352
CGP Rm L5-139

Credit Hours: 
8:00 pm




August 31

No lecture; assign review articles 


September 7

Heat Shock Proteins

Michelle Messmer

September 14   

Cytokine Microenvironment in Tumors

Dan Fisher

September 21

Immune cell metabolism

Scott Olejniczak

September 28 

Cytosolic Sensors of Viral Infection Regulating Type I Interferon Induction

Danuta Kozbor


October 5

Regulatory T cells and their role in Tumor Immunology

Joseph Barbi

October 12

Dendritic Cells & Cancer Immunotherapy

Aimin Jiang

October 19

Adoptive TCR-engineered T cell therapy

Richard Koya

October 26

No Class; Upstate Immunology Conference (10/25-28)


November 2       

Monocyte/Macrophage Plasticity in the Tumor Microenvironment

Jason Muhitch

November 9

Checkpoint Inhibition

Joseph Skitzki

November 16


November 23

No Class; Thanksgiving

November 30

Student Presentation


December 7

Student Presentation; Ethics Discussion


December 14

No Class; Final exam week