Class of 2015

Pongwut Danchaivijitr, MD

Education and Training
Faculty of Medicine, Siriraj Hospital, Thailand

Residency
Greater Baltimore Medical Center, Baltimore, MD

Publications
Danchaivijitr P, Yared J, Rapoport AP. Successful treatment of IgG and complement-mediated autoimmune hemolytic anemia (AIHA) with bortezomib and low-dose cyclophosphamide. Am J Hematology 2011 Mar;86(3):331-2.

Sofia Ghani, MD

Education and Training
Ayub Medical College, University of Peshawar, Pakistan

Residency
New York Methodist Hospital, Brooklyn, NY

Publications
Periorbital necrobiotic xanthogranuloma treated successfully with novel multiple myeloma therapy. Ghani S, Al Ustwani O, Khalid B, Bogner P, Grassi M, Powell J, Bhat SA. Clin Adv Hematol Oncol 2013 Oct;11(10):678-80

Abstracts
The impact of cigarette smoking on treatment outcome in metastatic pancreatic cancer patients. S Ghani, P Jiawatanarat, K Chittawatanarat, S Samuel, RV Iyer, W W Ma; Roswell Park Cancer Institute, Buffalo, NY; Chiang Mai University, Chiang Mai, Thailand; University at Buffalo, Buffalo, NY; 2014 ASCO Annual Meeting; J Clin Oncol 32,2014 (suppl; abstr e15183)

Evaluation of prostate specific antigen (PSA) response following abiraterone in metastatic, castration resistant prostate cancer (mCRPC) previously treated with ketoconazole compared to ketoconazole naïve patients: A retrospective review. S Ghani, K Attwood, A Elefante, K Khalid, D L Trump; Roswell Park Cancer Institute, Buffalo, NY; University at Buffalo, The State University of New York, Buffalo, NY. J Clin Oncol 32, 2014 (suppl; abstr e16067) 2014 ASCO Annual Meeting

Hassan Hatoum, MD

Education and Training
Kursk State Medical University, Russian Federation

Residency
Staten Island University Hospital, Staten Island, NY
American University of Beirut, Beirut, Lebanon (Hematology and Oncology, Internal Medicine)
Makassed General Hospital, Beirut, Lebanon

Publications
Hatoum HA, Mahfouz RA, Otrock ZK, Hudaib AR, Taher AT, Shamseddine AI. Acute myeloid leukemia with T-cell receptor gamma gene rearrangement occurring in a patient with chronic lymphocytic leukemia: a case report. Am J Hematology 2007 Jan;82(1):69-72.

Otrock ZK, Hatoum HA, Salem ZM. Acute tumor lysis syndrome after rituximab administration in Burkitt's lymphoma. Intern Emerg Med. 2008 Jun;3(2):161-3.

Otrock ZK, Hatoum HA, Uthman IW, Taher AT, Saab S, Shamseddine AI. Non-Hodgkin's lymphoma in a woman with adult-onset Still's disease: a case report. J Med Case Rep. 2008 Mar 6;2:73

Otrock ZK, Hatoum HA, Salem ZM, Tawil A, Mahfouz RA, Zaatari GS, Bazarbachi A. Long-term remission in a patient with hepatosplenic gamma delta T cell lymphoma treated with bortezomib and high-dose CHOP-like chemotherapy followed by autologous peripheral stem cell transplantation. Ann Hematol. 2008 Dec;87(12):1023-4.

Farhat MH, Barada KA, Tawil AN, Itani DM, Hatoum HA, Shamseddine AI. Effect of mucin production on survival in colorectal cancer: a case-control study. World J Gastroenterol 14(45):6981-5.

Otrock ZK, Hatoum HA, Awada AH, Ishak RS, Shamseddine AI. Hypoxia-inducible factor in cancer angiogenesis: structure, regulation and clinical perspectives. Crit Rev Oncol Hematol. 2009 May;70(2):93-102.

Hatoum HA, Habib JG, Tawil A, Chakhachiro Z, Otrock ZK, Husari A, Shamseddine A. Adenocarcinoma of the lunc presenting as a metastatic tongue mass. South Med J. 2008 Jul;101(7):770-1.

Kchour G, Tarhini M, Kooshyar MM, El Hajj H, Wattel E, Mahmoudi M, Hatoum H, Rahimi H, Maleki M, Rafatpanah H, Rezaee SA, Yazdi MT, Shirdel A, de Thé H, Hermine O, Farid R, Bazarbachi A. Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL).Blood. 2009 Jun 25;113(26):6528-32.

Musallam KM, Jamali FR, Hatoum HA, Seoud M, El-Saghir NS, Shamseddine AI. Axillary lymph node ratio revisited. J Clin Oncol. 2009 Aug 20;27(24):e67; author reply e68-9. Epub 2009 Jul 20.

Hatoum HA, Jamali FR, El-Saghir NS, Musallam KM, Seoud M, Dimassi H, Abbas J, Khalife M, Boulos FI, Tawil AN, Geara FB, Salem Z, Shamseddine AA, Al-Feghali K, Shamseddine AI. Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positive breast cancer. Ann Surg Oncol. 2009 Dec;16(12):3388-95.

Hatoum HA, Jamali FR, El-Saghir NS, Musallam KM, Seoud M, Dimassi H, Abbas J, Khalife M, Boulos FI, Tawil AN, Geara FB, Salem Z, Shamseddine AA, Al-Feghali K, Shamseddine AI. Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positive breast cancer. Indian J Surg Oncol. 2010 Jan;1(1):68-75.

Charafeddine KM, Hatoum HA, Otrock ZK, Mahfouz RA, Salem ZM, Shamseddine AI, Taher AT, El-Saghir NS, Bazarbachi A. Long-term outcome of adult acute lymphoblastic leukemia in Lebanon: a single institution experience from the American University of Beirut. Hematol Oncol Stem Cell Ther. 2009;2(2):333-9.

Otrock ZK, Hatoum HA, Musallam KM, Awada AH, Shamseddine AI. Is VEGF a predictive biomarker to anti-angiogenic therapy? Crit Rev Oncol Hematol. 2011 Aug;79(2):103-11.

Hatoum HA, Abi Saad GS, Otrock ZK, Barada KA, Shamseddine AI. Metastasis of colorectal carcinoma to the testes: clinical presentation and possible pathways. Int J Clin Oncol. 2011 Jun;16(3):203-9.

Hatoum HA,HJamali FR, El-Saghir NS, Musallam KM, Seoud M, Dimassi H, Abbas J, Khalife M, Boulos FI, Tawil AN, Geara FB, Salem Z, Shamseddine AA, Al-Feghali K, Shamseddine AI. Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positive breast cancer. Indian J Surg Oncol. 2010 Dec;1(4):305-12.

El Saghir NS, Tfayli A, Hatoum HA, Nachef Z, Dinh P, Awada A. Treatment of metastatic breast cancer: state-of-the-art, subtypes and perspectives. Crit Rev Oncol Hematol. 2011 Dec;80(3):433-49.

Azab B, Torbey E, Hatoum H, Singh J, Khoueiry G, Bachir R, McGinn JT Jr, McCord D, Lafferty J. Usefulness of red cell distribution width in predicting all-cause long-term mortality after non-ST-elevation myocardial infarction. Cardiology 2011;119(2):72-80.

Farhat FS, Temraz S, Kattan J, Ibrahim K, Bitar N, Haddad N, Jalloul R, Hatoum HA, Nsouli G, Shamseddine AI. A phase II study of lipoplatin (liposomal cisplatin)/vinorelbine combination in HER-2/neu-negative metastatic breast cancer. Clin Breast Cancer. 2011 Dec;11(6):384-9.

Harris K, Khachaturova I, Azab B, Maniatis T, Murukutla S, Chalhoub M, Hatoum H, Kilkenny T, Elsayegh D, Maroun R, Alkaied H. Small cell lung cancer doubling time and its effect on clinical presentation: a concise review. Clin Med Insights Oncol. 2012;6:199-203.

Gupta N, Gupta S, Al Ustwani O, Hatoum H, Bhat S. Bing-Neel Syndrome in a patient with Waldenstrom's Macroglobinemia: A Challenging Diagnsos in the face of normal brain imaging. CNS Neurosci Ther 2014 Aug 8 (epubliation ahead of print)

Gupta N, Gupta S, Gandhi S, Hatoum H, Dy G. Critical acral ischemia leading to multiple finger amputation: side effects of long-term (>30 cycles) pemetrexed maintenance treatment in a patient. Br J Clin Pharmacol 2014 June 24 (epublicaiton ahead of print)

Gupta N, Hatoum H, Dy G. First line treatment of advanced non-small cell lung cancer- specific focus on albumin bound paclitaxel. Int J Nanomedicine 9: 209-21, 2014.

Venkata Pokuri, MD

Education and Training
Gandhi Medical College, Secunderabad, India

Residency
St. Luke's-Roosevelt Hospital Center, Columbia University College of Physicians & Surgeons, New York, NY

Publications
Venkata Pokuri, Shipra Gandhi, Junaid Baqai, Mihai Merzianu, Seema Bhat. Interdigitating Dendritic Cell Sarcoma: A Case Report and Review of Literature. Accepted for publication in JNCCN, 2014 (in press).

Pokuri V, Sule N, Soofi Y, Xu B, Guru K, George S. A case of unusual mast cell response with interstitial cystitis-like symptoms to neoadjuvant chemotherapy for muscle-invasive transitional cell carcinoma of the bladder. J Natl Compr Canc Netw. 2013 Dec 1; 11(12):1459-63.

Gamboa EO, Pokuri V, Batra R, Varma M. Pain in the butt: marginal zone lymphoma of the gluteus muscle. J Clin Oncol. 2012 Mar 1; 30(7):e86-7

Neha Gupta, Omar Al Ustwani, Venkata Pokuri, Bhat Seema. Bing-Neel Syndrome in a Patient with Waldenstrom’s Macroglobulinemia: A Challenging Diagnosis in the Face of Normal Brain Imaging. Accepted for publication in CNS Neuroscience and Therapeutics, 2014.

Dy I, Pokuri V, Olichney J, Wiernik P. Levamisole-adulterated in cocaine causing agranulocytosis, vasculopathy, and acquired protein S deficiency. Ann Hematol. 2012 Mar; 91(3):477-8

Abstracts
Venkata K. Pokuri, Johar R. Syed, Zhengyu Yang, Erinn P. Field, Roberto Pili, Ellis Glenn Levine, Donald L. Trump, Alan Hutson, Khurshid Guru, Saby George. Predictors of complete pathological response (pT0) to neoadjuvant chemotherapy (NAC) in muscle-invasive bladder carcinoma (MIBC). Abstract published in ASCO/JCO, 2014.

V.Pokuri, C.Albany, G.Psevdos, J.Paredes, M.Grossbard, V.Sharp. A Seven-Year review of AIDS and Non-AIDS related malignancies in a large HIV/AIDS center in New York; St. Luke’s-Roosevelt Hospital. Presented at 49th Annual Meeting of IDSA (Infectious Diseases Society of America), Boston, 2011

Gajria D, Pokuri V, Steingart R, Hudis C, Dang C. Symptomatic congestive heart failure after neo/adjuvant dose-dense epirubicin- A retrospective analysis of two trials with long-term follow up; Memorial Sloan-Kettering Cancer Center. Presented at San Antonio Breast Cancer Symposium, 2010

Venkata K. Pokuri, Young Im Lee, Santhosh Devarapally, Raj Dasgupta, Liliana Rios, George McKinley. Immune Reconstitution Inflammatory Syndrome induced systemic Kaposi sarcoma involving Liver. NYACP, 2010

Venkata K. Pokuri, Santhosh Reddy Devarapally. Hepatic Sarcoidosis And Nonalcoholic Steatohepatitis (NASH): A Less Recognized Combination. NYACP, 2010

Gayatri Vaidyanathan, MD

Education and Training
Gandhi Medical College, Bhopal, India

Residency
SUNY, University at Buffalo, Buffalo, NY

Publications
Follicular lymphoma Grade 3, updates and Review. Vaidyanathan G, Czuczman, M. Clin Lymphoma Myeloma Leuk. 2014 June. IMID 25066038

Toxicities of targeted therapies and their amangement. Vaidyanathan G, Dy G. International journal of targeted thereapy, 2014 June

Clinical spectrum and prognosis of follicular lymphoma with blastoid transformation: Case series and review of literature. Vaidyanathan G, Hernandez F. Ann Hematolo 2001 Aug;90(8):955-62

Stop and go FOLFOX Bevacizumab Chemotherapy in the First Line treatment of Metastatic Colorectal Cancer. Vaidyanathan G, Fakih, M. Oncology. 2010;79(1-2):67-71. Epub 2010 Nov 12

A case of curative - Intent hepatectomy for colon cancer metastatic to the scapula and liver. Vaidyanathan G, Fakih M. Anticancer Res. 2010 Feb;30(2):677-9

Abstracts
Stop and go FOLFOX Bevacizumab Chemotherapy in the First Line treatment of Metastatic Colorectal Cancer. Vaidyanathan G, Fakih, M. Poster presented at NYACP, Rochester Nov 2010

Peter F. Schnatz, Gayatri Vaidyanathan, Ann-Marie Surette, Mark Tower, Cynthia Price, Krishnamurthy Sundaram. The Medical Needs and Demographic Makeup of Menopausal Women in a Rural Nigerian Village. Annual NAMS Meeting, Orlando Florida, Sept 2008

Yang Wang, MD

Education and Training
Tongji Medical University, China

Residency
Mt. Vernon Hospital, Mt. Vernon, NY

Publications
Carreño R, Brown WS, Li D, Hernandez JA, Wang Y, Kim TK, Craft JW Jr, Komanduri KV, Radvanyi LG, Hwu P, Molldrem JJ, Legge GB, McIntyre BW, Ma Q. 2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second generation monoclonal antibody selectively targeting activated LFA-1 J Biol Chem. 2010 Oct 22;285(43):32860-8.

Wang Y, Li D, Nurieva R, Yang J, Sen M, Carreño R, Lu S, McIntyre BW, Molldrem JJ, Legge GB, Ma Q. LFA-1 affinity regulation is necessary for the activation and proliferation of naive T cells. J Biol Chem. 2009 May 8;284(19):12645-53.

Perchellet EM, Wang Y, Lou K, Zhao H, Battina SK, Hua DH, Perchellet JP. Antitumor triptycene analogs directly interact with isolated mitochondria to rapidly trigger markers of permeability transition. Anticancer Res. 2007 Sep-Oct;27(5A):3259-71.

Perchellet EM, Wang Y, Lou K, Zhao H, Battina SK, Hua DH, Perchellet JP. Novel substituted 1,4-anthracenediones with antitumor activity directly induce permeability transition in isolated mitochondria. Int J Oncol. 2007 Nov;31(5):1231-41.

Hua DH, Lou K, Battina SK, Zhao H, Perchellet EM, Wang Y, Perchellet JP. Syntheses, molecular targets and antitumor activities of novel triptycene bisquinones and 1,4-anthracenedione analogs. Anticancer Agents Med Chem. 2006 Jul;6(4):303-18. Review.

Wang Y, Perchellet EM, Ward MM, Lou K, Zhao H, Battina SK, Wiredu B, Hua DH, Perchellet JP. Antitumor triptycene analogs induce a rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria. Int J Oncol. 2006 Jan;28(1):161-72.

Wang Y, Perchellet EM, Ward MM, Lou K, Hua DH, Perchellet JP. Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones. Anticancer Drugs. 2005 Oct;16(9):953-67.

Perchellet EM, Wang Y, Weber RL, Lou K, Hua DH, Perchellet JP. Antitumor triptycene bisquinones induce a caspase-independent release of mitochondrial cytochrome c and a caspase-2-mediated activation of initiator caspase-8 and -9 in HL-60 cells by a mechanism which does not involve Fas signaling.Anticancer Drugs. 2004 Nov;15(10):929-46.

Perchellet EM, Wang Y, Weber RL, Sperfslage BJ, Lou K, Crossland J, Hua DH, Perchellet JP. Synthetic 1,4-anthracenedione analogs induce cytochrome c release, caspase-9, -3, and -8 activities, poly(ADP-ribose) polymerase-1 cleavage and internucleosomal DNA fragmentation in HL-60 cells by a mechanism which involves caspase-2 activation but not Fas signaling. Biochem Pharmacol. 2004 Feb 1;67(3):523-37.

Wang B, Perchellet EM, Wang Y, Tamura M, Hua DH, Perchellet JP. Antitumor triptycene bisquinones: a novel synthetic class of dual inhibitors of DNA topoisomerase I and II activities. Anticancer Drugs. 2003 Aug;14(7):503-14. Revie

Wang Y, Perchellet EM, Tamura M, Hua DH, Perchellet JP. Induction of poly(ADP-ribose) polymerase-1 cleavage by antitumor triptycene bisquinones in wild-type and daunorubicin-resistant HL-60 cell lines. Cancer Lett. 2002 Dec 15;188(1-2):73-83.

Perchellet EM, Sperfslage BJ, Wang Y, Huang X, Tamura M, Hua DH, Perchellet JP. Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro. Anticancer Drugs. 2002 Jul;13(6):567-81.

Wang Y, Li D, Jones D, Bassett R, Sale GE, Khalili J, Komanduri KV, Couriel DR, Champlin RE, Molldrem JJ, Ma Q. Blocking LFA-1 activation with lovastatin prevents graft-versus-host disease in mouse bone marrow transplantation. Biol Blood Marrow Transplant. 2009 Dec;15(12):1513-22.

Ma Q, Wang C, Jones D, Quintanilla KE, Li D, Wang Y, Wieder ED, Clise-Dwyer K, Alatrash G, Mj Y, Munsell MF, Lu S, Qazilbash MH, Molldrem JJ. Adoptive transfer of PR1 cytotoxic lymphocytes associated with reduced leukemia burden in a mouse acute myeloid leukemia xenograft model. Cytotherapy 2010 Dec;12(8):1056-62.