Tamibarotene Plus Venetoclax/Azacitidine in Participants With Newly Diagnosed AML


Study Number
1397721
Phase
II
Age Group
Adult
Purpose

Tamibarotene is being studied as a treatment for participants with a type of leukemia called acute myeloid leukemia, or AML for short. Tamibarotene is being studied as a treatment for participants with AML whose cancer has a specific genetic abnormality characterized by the overexpression of the retinoic acid receptor alpha (RARA) gene. This genetic profile is found in about 3 of every 10 people with AML. During the trial, tamibarotene will be given with 2 other drugs that are already used together to treat people who have AML and who cannot start treatment with standard chemotherapy.

Full Title

SY-1425 in Combination with Venetoclax and Azacitidine in Adult Patients with
RARA-positive, Previously Untreated AML Who Are Ineligible for Standard Induction Therapy

ClinicalTrials.Gov ID
NCT04905407

To inquire about participating in these studies, call 1-800-ROSWELL (1-800-767-9355) or e-mail askroswell@roswellpark.org.