Available Clinical Trials

To inquire about participating in these studies, call 1-877-ASK-RPCI (1-877-275-7724). E-mail: askrpci@roswellpark.org
 

A Phase 1B, Open Label, Dose Finding Study to Evaluate Safety, Pharmacokinetics and Pharmacodynamics of Axitinib(AG-013736) in Combination with MK-3475 in Patients with Advanced Renal Cell Cancer
Principal Investigator: George, Saby
A Pilot Study of Feasibility of Performing Intravital Microscopy in Melanoma Patients
Principal Investigator: Skitzki, Joseph J
OAG and Decitabine for Newly Diagnosed Acute Myeloid Leukemia Patients Greater than or Equal to 65 Years of Age
Principal Investigator: Wetzler, Meir
A Phase 1b Dose Escalation Study of Vantictumab (OMP-18R5) in Combination with Docetaxel in Patients with Previously Treated Recurrent or Advanced Non-Small Cell Lung Cancer
Principal Investigator: Dy, Grace K
A Phase I/II Study of Oral Calcitriol in Combination with Ketoconazole in Androgen Independent Prostate Cancer
Principal Investigator: George, Saby
(GOG 9923) A Phase I Study of Intravenous Carboplatin/Paclitaxel or Intravenous and Intraperitoneal Paclitaxel/Cisplatin in Combination with Continuous or Intermittent/CTEP-Supplied Agent ABT-888 (NSC# 737664) and CTEP-Supplied Agent Bevacizumab (...
Principal Investigator: Lele, Shashikant B
(RU021212I) Randomized Phase II Double Blind Study of Adjuvant Regorafenib vs Placebo in Patients with Node Positive Esophageal Cancer that Completed Pre-Operative Therapy
Principal Investigator: Malhotra, Usha
A Phase II Randomized, Open Label, Study of Sipuleucel-T vs. Sipuleucel-T and Tasquinimod in Patients with Metastatic Castrate-Resistant Prostate Cancer (CRPC)
Principal Investigator: Pili, Roberto
A Phase I/IIa, Open Label, Clinical Trial Evaluating the Safety and Efficacy of Autologous T Cells Expressing Enhanced TCRs Specific for NY-ESO-1/LAGE-1 in Patients with Recurrent or Treatment Refractory Ovarian Cancer
Principal Investigator: Odunsi, Adekunle O
Phase I Dose-Finding Study of Eltrombopag Following High Dose Cytarabine and Mitoxantrone in Relapsed/Refractory Patients with Acute Myeloid Leukemia
Principal Investigator: Wetzler, Meir
(E4512 )A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein
Principal Investigator: Chen, Hongbin
(A081105) Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)
Principal Investigator: Dy, Grace K
(A151216) Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)
Principal Investigator: Dy, Grace K
(COG ALTE11C1) Longitudinal Assessment of Ovarian Reserve in Adolescents with Lymphoma
Principal Investigator: Rokitka, Denise A
(A221301) OLANZAPINE for the Prevention of Chemotherapy Induced Nausea and Vomiting (CINV) in Patients Receiving Highly Emetogenic Chemotherapy (HEC): A Randomized, Double-Blind, Placebo-Controlled Trial
Principal Investigator: Levine, Ellis G
(E2112) A Randomized Phase III Trial of Endocrine Therapy plus Entinostat/Placebo in Postmenopausal Patients with Hormone Receptor-Positive Advanced Breast Cancer
Principal Investigator: Levine, Ellis G
(BMT CTN 1205) Easy to Read Informed Consent (ETRIC) for Hematopoietic Cell Transplantation Clinical Trials
Principal Investigator: Ross, Maureen
(UPCC 14153) A Randomized Phase II Trial of Radical Pleurectomy and Post-Operative Chemotherapy With or Without Intraoperative Porfimer Sodium-Mediated Photodynamic Therapy for Patients with Epithelioid Malignant Pleural Mesothelioma
Principal Investigator: Demmy, Todd L
A Dose-Regimen Finding Study to Evaluate Safety, Tolerability, Pharmacokinetics and Activity of Oraxol in Subjects with Advanced Malignancies
Principal Investigator: Ma, Wen Wee
Filgrastim-Mobilized Peripheral Blood Stem Cells for Allogeneic Transplantation with Unrelated Donors (NMDP IRB 1996-005; IRB-1999-0021)
Principal Investigator: McCarthy, Philip L
Cytogenic Studies in Acute Leukemia and Multiple Myeloma
Principal Investigator: Wetzler, Meir
(CHOB 570) A COG Soft Tissue Sarcoma Biology and Banking Protocol
Principal Investigator: Brecher, Martin
(CA-ALT-803-02-13) A Study of ALT-803 in Patients with Relapsed or Refractory Multiple Myeloma
Principal Investigator: Holstein, Sarah A
A Randomized Phase II Study of Sequential Biotherapy with Aflibercept and High Dose IL-2 versus High Dose IL-2 Alone in Patients with Inoperable Stage III or Stage IV Melanoma: Efficacy and Biomarker Study
Principal Investigator: Khushalani, Nikhil I
A Dose-Regimen Finding Study to Evaluate Safety, Tolerability, Pharmacokinetics and Activity of Oratecan in Subjects with Advanced Malignancies
Principal Investigator: Ma, Wen Wee
(NSABP B-52) A Randomized Phase III Trial Evaluating Pathologic Complete Response Rates in Patients with Hormone Receptor-Positive, HER2-Positive, Large Operable and Locally Advanced Breast Cancer Treated with Neoadjuvant Therapy of Docetaxel, Car...
Principal Investigator: Levine, Ellis G
A Phase I, Multi-Center, Non-Randomized, Open Label, Parallel-Group Study Evaluating the Pharmacokinetics and Safety of Regorafenib (BAY 73-4506) in Cancer Subjects with Severe Renal Impairment compared to a Control Group
Principal Investigator: Dy, Grace K
A Phase I Study of Ceritinib (LDK378), a Novel ALK Inhibitor, in Combination with Gemcitabine-Based Chemotherapy in Patients with Advanced Solid Tumors
Principal Investigator: Ma, Wen Wee
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Idelalisib (GS-1101) in Combination with Bendamustine and Rituximab for Previously Treated Indolent Non-Hodgkin Lymphomas
Principal Investigator: Czuczman, Myron S
(CX-839-003) A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamices of Escalating Oral Doses of the Glutaminase Inhibitor CB-839 in Patients with Relapsed and/or Treatment-Refractory Leukemia
Principal Investigator: Wang, Eunice S
Phase I Study of Oral PQR309 in Patients with Advanced Solid Tumors
Principal Investigator: Adjei, Alex
(GO28915) A Phase III, Open-Label, Multicenter, Randomized Study to Investigate the Efficacy and Safety of MPDL3280A (ANTI-PD-L1 ANTIBODY) Compared with Docetaxel In Patients with Non Small Cell Lung Cancer After Platinum Failure with Platinum-C...
Principal Investigator: Chen, Hongbin
(RU2612061) Randomized Phase II Study of AB (nab-paclitaxel [Abraxane], Bevacizumab) versus Ipilimumab for 1st Line Therapy of Unresectable Stage IV Metastatic Malignant Melanoma (BRAF V600E Negative)
Principal Investigator: Khushalani, Nikhil I
(A041-04) A Phase 2 Randomized, Double -Blind Study of Dalantercept Plus Axitinib Compared to Placebo Plus Axitinib in Patients with Advanced Renal Cell Carcinoma
Principal Investigator: Pili, Roberto
Phase I/II Study of Carfilzomib plus Rituximab plus Ifosfamide plus Carboplatin plus Etoposide (C-R-ICE) in Patients with Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Principal Investigator: Czuczman, Myron S
A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)
Principal Investigator: Adjei, Alex
(KX02-01-13) A Phase 1 Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetics of KX2-361 in Subjects with Advanced Malignancies that are Refractory to Conventional Therapies
Principal Investigator: Zhao, Yujie
(GU12-160) A Randomized Phase 2 Study Comparing Docetaxel Alone to Docetaxel in Combination with OGX-427 in Patients with Relapsed or Refractory Metastatic Urothelial Carcinoma after Receiving a Platinum-containing Regimen
Principal Investigator: Pili, Roberto
Two Versus Four Times-Weekly ALTENS for Treatment of Radiation-Induced Xerostomia: A Pilot Study
Principal Investigator: Singh, Anurag K
(COG ACNS0332) Efficacy of Carboplatin Administered Concomitantly with Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients
Principal Investigator: Fitzpatrick, Lorna
(BAY 1129980/16044) An Open-Label Phase I Dose-Escalation Study to Evaluate the Safety, Tolerability, Maximum Tolerated Dose, Pharmacokinetics, and Pharmacodynamics of the Anti-C4.4a Antibody Drug Conjugate BAY 1129980 in Subjects With Advanced So...
Principal Investigator: Adjei, Alex
(08-02) A Phase 1, Dose-Escalation Study of the Safety, Pharmacokinetics and Efficacy of Weekly Intravenous Briciclib in Patients with Advanced Solid Tumors
Principal Investigator: Ma, Wen Wee
(E1412) Randomized Phase II Open Label Study of Lenalidomide R-CHOP (R2CHOP) vs RCHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone) in Patients with Newly Diagnosed Diffuse Large B Cell Lymphoma
Principal Investigator: Hernandez-Ilizaliturri, Francisco J
(Alliance A011104/ACRIN 6694) Effect of Preoperative Breast MRI on Surgical Outcomes, Costs and Quality of Life of Women with Breast Cancer
Principal Investigator: Levine, Ellis G
(AC220-007) A Phase 3 Open-Label Randomized Study of Quizartinib (AC220) Monotherapy Versus Salvage Chemotherapy in Subjects with FLT3-ITD Positive Acute Myeloid Leukemia (AML) Refractory to or Relapsed After First-Line Treatment With or Without H...
Principal Investigator: Wang, Eunice S
A Phase 1 Open Label, Multicenter, Multiple Ascending Dose Trial Evaluating the Safety, Tolerability and Immunogenicity of Intramuscular Recombinant NY-ESO-1 Protein with GLA-SE Adjuvant in Patients with Unresectable or Metastatic Cancer Expressin...
Principal Investigator: Odunsi, Adekunle O
Interstitial Photodynamic Therapy during Standard Chemotherapy for Palliation of Patients with Head and Neck Squamous Cell Carcinoma - Phase II
Principal Investigator: Arshad, Hassan
A Cohort Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS)
Principal Investigator: Levine, Ellis G
The Effect of Bortezomib on Antibody Titers Against Common Viral and Vaccine Antigens
Principal Investigator: Lee, Kelvin
A Phase 2, Randomized, Multicenter Study of PEGPH20 (PEGylated Recombinant Human Hyaluronidase) Combined with nab-Paclitaxel Plus Gemcitabine Compared With nab-Paclitaxel Plus Gemcitabine in Subjects With Stage IV Previously Untreated Pancreatic C...
Principal Investigator: Ma, Wen Wee
A Phase II Study of the Combination of Aflibercept (VEGF-Trap) plus Modified FOLFOX 6 in Patients with Previously Untreated Metastatic Colorectal Cancer
Principal Investigator: Ma, Wen Wee
N1048 PROSPECT**) A Phase II/III Trial of Neoadjuvant FOLFOX with Selective Use of Combined Modality Chemoradiaiton Versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection...
Principal Investigator: Nurkin, Steven J
(1137-101) A Phase I Trial of CBL0137 in Patients with Advanced Solid Neoplasms
Principal Investigator: Ma, Wen Wee
(RTOG 1216) Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered with Concurrent Cisplatin versus Docetaxel versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer of the Head and Neck
Principal Investigator: Singh, Anurag K
(COG ACCL1131) A Phase III Open-Label Trial of Caspofungin vs. Azole Prophylaxis for Patients at High-Risk for Invasive Fungal Infections (IFI) Following Allogenetic Hematopoietic Cell Transplantation (HCT)
Principal Investigator: Bambach, Barbara J
(SWOG S1203) A Randomized Phase III Study of Standard Cytarabine plus Daunorubicin (7+3) Therapy or Idarubicin with High Dose Cytarabine (IA) Versus IA with Vorinostat (IA+V) in Younger Patients with Previously Untreated Acute Myeloid Leukemia (AML)
Principal Investigator: Wang, Eunice S
Neoadjuvant AGS-003 Immunotherapy in Patients with Localized Kidney Cancer <pT2
Principal Investigator: Schwaab, Thomas
A Pilot Study of the Immunological Effects of Neo-Adjuvant INCB024360 in Patients with Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Carcinoma
Principal Investigator: Odunsi, Adekunle O
(SWOG S1202) A Randomized Placebo-Controlled Phase III Study of Duloxetine for Treatment of Aromatase Inhibitor (AI)-Associated Musculoskeletal Symptoms in Women with Early Stage Breast Cancer
Principal Investigator: Levine, Ellis G
(GOG 0213) A Phase III Randomized Controlled Clinical Trial of Carboplatin and Paclitaxel (Or Gemcitabine) Alone or in Combination with Bevacizumab (NSC #704865, IND #113912) Followed by Bevacizumab and Secondary Cytoreductive Surgery in Platinum-...
Principal Investigator: Lele, Shashikant B
Feasibility of an Exercise Intervention to Enhance Fitness and QOL Among Adult Survivors of Childhood Cancer
Principal Investigator: Rokitka, Denise A
Ex Vivo Optical Imaging For Evaluation Of Tissue Obtained By Transbronchial Biopsies Of Peripheral Lung Lesions
Principal Investigator: Harris, Kassem N
A Phase I/IIb Study of DEC205mAb-NY-ESO-1 Fusion Protein (CDX-1401) Given with Adjuvant Poly-ICLC in Combination with INCB024360 for Patients in Remission with Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma Whose Tumors Expres...
Principal Investigator: Odunsi, Adekunle O
(A011202) A Randomized Phase III Trial Evaluating the Role of Axillary Lymph Node Dissection in Breast Cancer Patients (cT1-3 NI) Who Have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy
Principal Investigator: Levine, Ellis G
A Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 232 in Adult Subjects With Relapsed/Refractory Acute Myeloid Leukemia
Principal Investigator: Wetzler, Meir
(Alliance A011106) ALTernate Approaches for Clinical Stage II or III Estrogen Receptor Positive Breast Cancer NeoAdjuvant TrEatment (ALTERNATE) in Postmenopausal Women: A Phase III Study
Principal Investigator: Levine, Ellis G
A Phase 1 Study of the Safety and Pharmacokinetics of Escalating Doses of AGS15E Given as Monotherapy in Subjects with Metastatic Urothelial Cancer
Principal Investigator: Pili, Roberto
(COG ANBL1221) A Phase II Randomized Trial of Irinotecan/Temozolomide with Temsirolimus (NSC# 683864, IND# 61010) or Chimeric 14.18 Antibody (ch14.18) (NSC# 623408, IND# 4308) in Children with Refractory, Relapsed or Progressive Neuroblastoma
Principal Investigator: Higman, Meghan
FGFR1 Amplification as A Predictor of Efficacy in A Biomarker-Driven Phase II Study of BIBF 1120 in Advanced Squamous Cell Lung Cancer Patients Who Have Failed Up to Two Prior Chemotherapeutic Regimens
Principal Investigator: Adjei, Alex
(COG ACNS0821) Temozolomide with Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865, BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, A COG Randomized Phase II Screening Trial
Principal Investigator: Fitzpatrick, Lorna
A Phase II Study of Single Agent Topoisomerase-I Inhibitor Polymer Conjugate, Etirinotecan Pegol (NKTR-102), in Patients with Relapsed Small Cell Lung Cancer
Principal Investigator: Adjei, Alex
Using Social Network Analysis to Study Cancer Screening Behaviors Among Adults in Western New York
Principal Investigator: Erwin, Deborah O
(SWOG S1216) A Phase III Randomized Trial Comparing Androgen Deprivation Therapy + TAK-700 With Androgen Deprivation Therapy + Bicalutamide in Patients With Newly Diagnosed Metastatic Hormone Sensitive Prostate Cancer
Principal Investigator: Levine, Ellis G
(BMT CTN 1202) Prospective Multi-Center Cohort for the Evaluation of Biomarkers Predicting Risk of Complications and Mortality Following Allogeneic HCT
Principal Investigator: McCarthy, Philip L
PNH Registry
Principal Investigator: Griffiths, Elizabeth A
A Phase I Study of Surgery Plus Intraoperative Photodynamic Therapy (PDT) with Temoporfin in Patients with Resectable Primary Non-Small Cell Lung Cancer (NSCLC) with Ipsilateral Thoracic Nodal (N1 or N2) or T3/T4 Disease
Principal Investigator: Nwogu, Chukwumere E
Multicenter Phase 1b/2 Study of Tivozanib in Patients with Advanced Inoperable Hepatocellular Carcinoma
Principal Investigator: Iyer, Renuka V
A Phase 1 Study of DEC205mAb-NY-ESO-1 Fusion Protein (CDX-1401) Given with Adjuvant PolyICLC in Conjunction with 5-Aza-2'Deoxycytidine (Decitabine) in Patients with MDS or Low Blast Count AML
Principal Investigator: Griffiths, Elizabeth A
(COG AAML1031) A Phase III Randomized Trial for Patients with de novo AML Using Bortezomib and Sorafenib (IND#114480; NSC#681239, NSC#724772) for Patients with High Allelic Ratio FLT3/ITD
Principal Investigator: Beaupin, Lynda K
A Pilot Study of the Flaxseed Effects on Hormones and Lignans: Role of Race, Genes, and Gut Microbiome
Principal Investigator: McCann, Susan E
A Phase 1B/2 Study to Evaluate the Safety and Efficacy of PF-04449913, an Oral Hedgehog Inhibitor, in Combination with Intensive Chemotherapy, Low Dose Ara-C, or Decitibine in Patients with Acute Myeloid Leukemia or High-Risk Myelodysplastic Synd...
Principal Investigator: Wang, Eunice S
Influence of Advertising Claim Presentation on Beliefs and Affective Associations Related to Tobacco Products
Principal Investigator: O'Connor, Richard J
A Phase I/ II Trial of Pazopanib Alternating with Bevacizumab in Treatment-Naive Metastatic Clear Cell Renal Cell Carcinoma Patients
Principal Investigator: George, Saby
A Phase I/Ib, Dose-Escalation and Expansion Study to Evaluate the Safety and Antitumor Activity of MED13617, a Human Monoclonal Antibody Directed Against ANG2, as a Single-Agent or in Combination Therapy in Adult Subjects with Advanced Solid Tumors
Principal Investigator: Zhao, Yujie
(COG AALL1131) A Phase III Randomized Trial for Newly Diagnosed High Risk B-Precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum
Principal Investigator: Brecher, Martin
A Randomized Phase III Study Comparing Conventional Dose Treatment Using a Combination of Lenalidomide, Bortezomib and Dexamethasone (RVD) to High-Dose Treatment with Peripheral Stem Cell Transplant in the Initial Management of Myeloma in Patients...
Principal Investigator: Holstein, Sarah A
A Pilot Study of Broccoli Sprout Extract in Patients with Invasive Breast Cancer
Principal Investigator: Young, Jessica S
Impact of Carbonyl Reductase 3 Genotype Status on Echocardiographic Measurements of Cardiomyopathy in Breast Cancer Patients Treated with Anthracyclines
Principal Investigator: O'Connor, Tracey L
(COG ANHL1131) Intergroup Trial for Children or Adolescents with B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients
Principal Investigator: Barth, Matthew J
Clinical Trial Methods for Assessing a Tobacco Product
Principal Investigator: Mahoney, Martin C
A Pilot Study of Stereotactic Body Radiation Therapy (SBRT) After TEMLA for Stage III and IV (Oligometastatic) Non-Small Cell Lung Cancer
Principal Investigator: Singh, Anurag K
Alternative Approaches for Nausea Control
Principal Investigator: O'Connor, Tracey L
Pilot: Impact of High-Dose, Single Fraction Radiation on Immunogenicity of Sipuleucel-T in Metastatic Castration Recurrent Prostate Cancer Patients
Principal Investigator: Schwaab, Thomas
Community-Based Research Opportunities for the Witness Project Network (CROWN)
Principal Investigator: Erwin, Deborah O
(R1400-ST-1113) Phase I Study of REGN1400 in Combination with Erlotinib or Cetuximab Administered in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC) or Head and Neck Cancer (SCCHN)
Principal Investigator: Adjei, Alex
A Phase I Trial of a Recombinant Human hsp110-gp100 Chaperone Complex Vaccine for Advanced Stage IIIB/C or IV Melanoma
Principal Investigator: Kane, John M
Immunologic Impact of Stereotactic Body Radiation Therapy (SBRT) in Renal Cell Carcinoma
Principal Investigator: Schwaab, Thomas
Efficacy and Safety of Two Comparable Single Low Doses of Rasburicase Followed by Allopurinol in Adult Patients with Malignancy
Principal Investigator: Wetzler, Meir
(CALGB 70807) The Men's Eating and Living (MEAL) Study: A Randomized Trial of Diet to Alter Disease Progression in Prostate Cancer Patients on Active Surveillance
Principal Investigator: Mohler, James L
A Phase II Trial of Reduced Intensity Allogenenic Stem Cell Transplantation With Fludarabine, Melphalan and low Dose Total Body Irradiation
Principal Investigator: Liu, Hong
KIR Genotyping for Unrelated Donor (URD) Selection Prior to Hematopoietic Cell Transplantation (HCT) for AML: Selecting a Favorable KIR Donor
Principal Investigator: Ross, Maureen
Examining Quality of Life Among Long-Term Survivors of Childhood Cancer
Principal Investigator: Rokitka, Denise A
Plasma Mitochondrial DAMPs in Patients Receiving Chemotherapy or Allogenetic Hematopoietic Stem Cell Transplantation
Principal Investigator: Segal, Brahm
(COG AEWS1031) A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma
Principal Investigator: Brecher, Martin
(CLR 10-23) A Phase I Pharmacokinetic and Safety Study of Paclitaxel Injection Concentrate for Nano-Dispersion (PICN) Alone and in Combination with Carboplatin in Subjects with Advanced Solid Malignancies
Principal Investigator: Ma, Wen Wee
A Correlative Study of Lung Cancer Treatment Response
Principal Investigator: Singh, Anurag K
(COG ACNS0831) Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Ages 1 to 21 Years
Principal Investigator: Fitzpatrick, Lorna
A Phase 1 Clinical Trial of mTOR Inhibition With Rapamycin for Enhancing Intranodal Dendritic Cell Vaccine Induced anti-Tumor Immunity In Patients with NY-ESO-1 Expressing Solid Tumors
Principal Investigator: Odunsi, Adekunle O
A Phase I Pharmacokinetic, Safety and Tolerability Study of Paclitaxel Injection Concentrate for Nano-Dispersion (PICN) Administered Weekly in Subjects with Advanced Solid Malignancies in US Population
Principal Investigator: Ma, Wen Wee
Evaluation of Pre-Operative Nutritional Risk as a Predictor of Post-Operative Outcome in Patients Undergoing Robot-Assisted Radical Cystectomy
Principal Investigator: Guru, Khurshid
Correlation of Deuterated Phenanthrene Metabolism with Bronchoepitheial Dysplasia and Metaplasia in Smokers at High Risk for Lung Cancer
Principal Investigator: Adjei, Alex
A Phase 1 and Pharmacologic Study of MM-151 in Patients with Refractory Advanced Solid Tumors
Principal Investigator: Adjei, Alex
A Pilot Study Evaluating NFAT, NFkB and, ERK 1/2 Nuclear Translocation as a Predictive Marker for Acute Graft-versus-Host Disease
Principal Investigator: Chen, George L
(COG ACCL0934) A Randomized Trial of Levofloxacin to Prevent Bacteremia in Children Being Treated for Acute Leukemia (AL) or Undergoing Hematopoietic Stem Cell Transplantation (HSCT)
Principal Investigator: Bambach, Barbara J
(COG ACCL0933) A Randomized Open-Label Trial of Caspofungin Versus Fluconazole to Prevent Invasive Fungal Infections in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)
Principal Investigator: Brecher, Martin
(CIBMTR 10-CBA) A Multicenter Access and Distribution Protocol for Unlicensed Cryopreseved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients with Hematologic Malignancies and Other Indications
Principal Investigator: McCarthy, Philip L
(SWOG S1007) A Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 positive Nodes, Hormone Receptor-Positive and HER2-Negative Breast Cancer with Recurrence Score (RS) of 25 or less
Principal Investigator: Levine, Ellis G
Predictive Markers of Response in a Phase II Trial of Axitinib in Advanced Melanoma
Principal Investigator: Khushalani, Nikhil I
(COG AAML08B1) Biology Study of Transient Myeloproliferative Disorder (TMD) in Children with Down Syndrome (DS)
Principal Investigator: Higman, Meghan
(COG ANHL04B1) Rare and Cutaneous Non-Hodgkin Lymphoma Registry
Principal Investigator: Brecher, Martin
Ofatumumab (O) in Combination With Chemotherapy: Hyper-Fractionated Cyclophosphamide, Doxorubicin, Vincristine and Dexamethasone (O-HyperCVAD) Alternating With Ofatumumab High-Dose Cytarabine and Methotrexate (O-MA) for Patients With Newly Diagn...
Principal Investigator: Hernandez-Ilizaliturri, Francisco J
Randomized Phase II Study of Epigenetic Priming Using Decitabine with Induction Chemotherapy in Patients with Acute Myelogenous Leukemia (AML)
Principal Investigator: Griffiths, Elizabeth A
Novel Risk Factors and Potential Early Detection Markers for Ovarian Cancer
Principal Investigator: Moysich, Kirsten B
A Phase I Clinical Trial of Oral Calcitriol with Fixed Dose of Cisplatin and Gemcitabine in Patients with Advanced Solid Tumors
Principal Investigator: Dy, Grace K
Pilot Study of Oral Calcitriol in Patients at High Risk for Lung Cancer
Principal Investigator: Adjei, Alex
(CALGB 140503) A Phase III Randomized Trial of Lobectomy Versus Sublobar Resection for Small (< 2 cm) Peripheral Non-Small Cell Lung Cancer
Principal Investigator: Nwogu, Chukwumere E
A Phase II Randomized Study of Stereotactic Body Radiation Therapy (SBRT) Regimes for Medically Inoperable Patients with Node Negative, Peripheral Non- Small Cell Lung Cancer
Principal Investigator: Singh, Anurag K
Easing the transition to Post-Treatment Status for Breast Cancer Patients
Principal Investigator: Hydeman, Jennifer A
Evaluation of Smoker Reactions to Novel Tobacco Products
Principal Investigator: Bansal Travers, Maansi
A Phase I Study of Targeted Lung Chemotherapy in the Treatment of Metastatic Tumors
Principal Investigator: Demmy, Todd L
(CALGB 90203) A Randomized Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation Prior to Radical Prostatectomy Versus Immediate Radical Prostatectomy in Patients with High-Risk, Clinically Localized Prostate Cancer -
Principal Investigator: Mohler, James L
(COG ANBL0032) Phase III Randomized Study of Chimeric Antibody 14.18 (Ch14.18) in High Risk Neuroblastoma Following Myeloablative Therapy and Autologous Stem Cell Rescue
Principal Investigator: Brecher, Martin
Lung Bronchoscopy Research Samples & Database
Principal Investigator: Reid, Mary E
Leukocyte Apheresis for Research
Principal Investigator: Lee, Kelvin
Women's Health After Breast Cancer Study
Principal Investigator: Hong, Chi-Chen
(COG ALTE03N1) Key Adverse Events After Childhood Cancer
Principal Investigator: Brecher, Martin
Intensity Modulated Radiation Therapy for Anal Cancer: Dosimetric Comparison, Acute Toxicity Profile, and Quality of Life Assessment
Principal Investigator: Mattson, David
Molecular Mechanisms Involved in Cancer Predisposition
Principal Investigator: Voian, Nicoleta C
(COG ALTE05N1) Umbrella Long-Term Follow-Up Protocol
Principal Investigator: Brecher, Martin
(COG AALL0932) Treatment of Patients with Newly Diagnosed Standard Risk B-Lymphoblastic Leukemia (B-ALL) or Localized B-lineage Lymphoblastic Lymphoma (B-LLy)
Principal Investigator: Brecher, Martin
(COG AALL08B1) Classification of Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)
Principal Investigator: Brecher, Martin
Exploring Current Smokers' Interest in Using Smokeless Tobacco Products Smokeless Tobacco Substitution for Cigarettes
Principal Investigator: Mahoney, Martin C
(COG AHEP0731) Treatment of Children with All Stages of Hepatoblastoma
Principal Investigator: Brecher, Martin
Genetic Signature for Progression of Barrett's Esophagus to Esophageal Adenocarcinoma. A Pilot Study
Principal Investigator: Nava, Hector R
Brody Belt
Principal Investigator: Guru, Khurshid
A Phase I Study of Oral Arsenic Trioxide with or without Ascorbic Acid in Adults with Myelofibrosis
Principal Investigator: Wetzler, Meir
A Phase I Study of the mTOR Inhibitor Temsirolimus in Combination with the HDAC Inhibitor Vorinostat in Patients with Metastatic Prostate Cancer
Principal Investigator: Pili, Roberto
Phase I Study of LBH589, A Novel Oral Deacetylase Inhibitor in Patients with Recurrent or Refractory Hodgkin or Non-Hodgkin's Lymphoma
Principal Investigator: Czuczman, Myron S
A Phase I/II Study of High Dose Interleukin 2, Aldesleukin, in Combination with the Histone Deacetylase Inhibitor Entinostat in Patients with Metastatic Renal Cell Carcinoma -
Principal Investigator: Pili, Roberto
Evaluation & Quality Assurance of the New York State Smokers' Quitline
Principal Investigator: Hyland, Andrew J
The National Marrow Donor Program Research Database for Allogeneic Unrelated Hematopoietic Stem Cell Transplantation and Marrow Toxic Injuries
Principal Investigator: McCarthy, Philip L
Collection of Blood from Healthy Donors and Patients with Non-Hodgkin's Lymphoma to Study the Immunological Activity of Peripheral Blood Mononuclear Cells (PBMC) and Human Serum
Principal Investigator: Czuczman, Myron S