(COG ACCL0934) A Randomized Trial of Levofloxacin to Prevent Bacteremia in Children Being Treated for Acute Leukemia (AL) or Undergoing Hematopoietic Stem Cell Transplantation (HSCT)

The open-label, randomized, controlled trial will evaluate whether prophylactic therapy with levofloxacin will decrease the incidence of bacteremia in pediatric patients being treated with intensive chemotherapy for acute leukemia or for those undergoing HSCT. In addition, the study designwill allow assessment of the potential risks of prophylactic therapy such as impact on host flora and quinolone-related musculoskeletal side effects.

Study Number: 

NCG 205811

Principal Investigator: 
ClinicalTrials.Gov ID: 

To inquire about participating in these studies, call 1-877-ASK-RPCI (1-877-275-7724) or e-mail askrpci@roswellpark.org.