(COG AAML08B1) Biology Study of Transient Myeloproliferative Disorder (TMD) in Children with Down Syndrome (DS)
Description: 

In this study, GATA1 mutations will be analyzed to determine their relationship to the TMD phenotype and to determine whether the presistence of a mutant GATA1 bearing clone can predict progression to AMkL. This study will correlate the relationship between the "historic" definitions of the TMD phenotype with advances in megakaryoblast biology and clinical predictors of outcome.

Study Number: 

NCG 201911

Phase: 
NT
Principal Investigator: 
ClinicalTrials.Gov ID: 
NCT00959283

To inquire about participating in these studies, call 1-877-ASK-RPCI (1-877-275-7724) or e-mail askrpci@roswellpark.org.