A Postdoctoral Fellow position is available in the laboratory of Dr. Ethan V. Abel in the Department of Molecular and Cellular Biology. Position offers independence as well as important collaborative opportunities. Research will focus on the functional characterization of transcriptional/epigenetic regulators and signaling proteins in pancreatic cancer, and how these cellular components regulate drug resistance, cancer stem cells, metastasis, and metabolism to drive the disease. The laboratory’s research places equal emphasis on basic, mechanistic discovery and translational/preclinical research. Regularly implemented techniques include protein biochemistry, tissue culture techniques (including primary cells and organoids), cell proliferation/cell cycle assays, apoptosis assays, flow cytometry, PCR, RT-PCR, human/mouse xenografts, chromatin immunoprecipitation (ChIP), ChIP-seq, RNA-seq, ATAC-seq, DNA cloning and lentivirus/adenovirus-based gene delivery. Multiple established projects are available. Self-motivated and detail-oriented individuals with appropriate training background in cell and molecular biology are encouraged to apply. Position is available immediately. Roswell Park Cancer Institute (RPCI) provides a state-of-the-art research environment that includes 23 research core facilities and active collaboration with clinical groups. RPCI is America’s first cancer center and the only National Cancer Institute (NCI)-designated Comprehensive Cancer Center in upstate New York.
The incumbent will directly assist the PI in the Department of Molecular and Cellular Biology at Roswell Park Comprehensive Cancer Center for conducting experiments for sponsored research funded by NIH and Foundation Grants. A high degree of integrity, organization and communication skills are required. The incumbent needs to be able to conduct research projects and design experiments independently. Supervision and on-the-job training will be provided in specific methods and techniques. The incumbent will train new personnel when necessary, must work well with others, and contribute to a diverse and interactive lab environment. The incumbent will need to participate in manuscript writing for publication; may assist in grant writing. Salary is commensurate with relevant research experience and NIH pay scale.
Required qualifications (as evidenced by an attached resume):
- PhD degree in biology, biochemistry, or related field.
- At least one first-author publication in peer-reviewed journals.
- Familiar with biochemical analysis, molecular and cell biological techniques, and working experience in cell culture techniques.
- Applicants should have no more than 2 years of postdoctoral experience.
Preferred qualifications:
Hands-on experience in flow cytometry in an academic laboratory setting and working experience with mice for tumor implantation/monitoring, drug treatment, biosample collection, and euthanasia is preferred but not absolutely required. Bioinformatic expertise is strongly desired.
Interested applicants are invited to submit 1) curriculum vitae and 2) contact information for three references to: Ethan.Abel@RoswellPark.org