Postdoctoral Position Cell Cycle Control in Cancer

Health Research Inc. (HRI) Roswell Park Division
Center for Personalized Medicine
Full Time
Commensurate with accumulated post doctoral research experience and NIH pay scale
Description of Duties

Postdoctoral position is open for highly motivated candidates in the laboratory of Dr. Erik Knudsen in the Center for Personalized Medicine, Roswell Park Comprehensive Cancer Center, NY- a National Cancer Institute (NCI) designated comprehensive cancer center. The Knudsen lab focuses on distinct features of the cell cycle including the RB-pathway, DNA replication control, and chromosome instability.  State of art facilities such as genomics, multiplexed imaging, and sophisticated cancer models are widely used in the laboratory. Multiple models systems, including Genetically Engineered Mouse Models (GEMMs), patient-derived xenograft (PDX), and syngeneic tumor models are used to address challenging mechanisms in cancer. Currently the laboratory is stably funded by multiple grants from NIH/NCI and other funding sources.


The postdoctoral position is focused on understanding fundamental feature of cell cycle control in disease cancer etiology, disease progression and as a therapeutic target.    Studies will involve multiple different approaches to study tumor biology in cell and animal models, complemented by the use of genomic approaches.


Ideal candidates will have experience with cancer research and have a track record of leading projects to publication.   Postdoctoral fellows will be expected to direct independent projects in a multi-disciplinary setting, assist in mentoring junior lab members, and apply for independent funding as appropriate.   A long-term goal of the project is to bring the research to clinical application and fellows will have the opportunity to directly contribute to clinical trial development and interactions with the multi-disciplinary teams.


The search is primarily targeted towards scientists who are completing their PhD or have recently graduated with first author publications demonstrating their skills in related areas of gene transcription, epigenetics, biochemistry, cancer biology, and immunology. Experience of working with mouse models of cancer will be preferred. The candidate should possess outstanding written and verbal communication skills.



1. PhD in a related discipline

2. Record of research accomplishment apparent in peer-reviewed publications

3. Self motivated with a positive attitude

4. Strong verbal and written communication skills

Applicant Instructions

Interested individuals should send a CV, statement of interest, and a list of three references to:
Erik Knudsen, PhD