Postdoctoral Fellowship in Immunotherapy

Health Research Inc. (HRI) Roswell Park Division
Cell Stress Biology
Full Time/Days
Commensurate with relevant research experience and NIH pay scale
Description of Duties

A postdoctoral position is open for a highly motivated candidate in the laboratory of Dr. Craig Brackett, Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo NY. Roswell Park is a National Cancer Institute (NCI) designated Comprehensive Cancer Center.

The overarching research of the Brackett lab is devoted to defining novel strategies to dampen stress response pathways as a means to augment antitumor immunity of toll-like-receptor 5 (TLR) agonists. State-of-the-art shared resources at Roswell such as Genomics, Comparative Oncology, and Flow and Image Cytometry are widely used in the laboratory. Multiple model systems such as implantable mouse models, carcinogen-induced mouse models, Genetically Engineered Mouse Models (GEMMs), and patient-derived culture systems are used to assess the ability of our TLR5 agonist entolimod to improve immunotherapy approaches that mirror standard-of-care immunotherapies used in the clinic. The laboratory is currently funded by the National Cancer Institute (NCI), Department of Defense (DoD), and industry.

This position is supported by an NIH-funded project that seeks to leverage the immune-enhancing and radioprotective properties of entolimod to improve liver-directed radiotherapy plus immune checkpoint inhibitor efficacy for liver metastasis.

Lab website:


The search is primarily targeted toward scientists who are completing their PhD or have recently graduated with first author publications. Experience working with mouse models and immunology-based techniques is preferred. The highly motivated candidate should be able to work independently, should possess outstanding written and verbal communication skills, and should have outstanding organizational skills.

Applicant Instructions

Interested applicants should send a cover letter highlighting your past research experience and interests, CV, and contact information for at least 3 references to Dr. Craig Brackett at