A Postdoctoral Fellow/Associate position is available in the laboratory of Dr. Hai Wang in the Department of Molecular and Cellular Biology at Roswell Park Comprehensive Cancer Center. The appointment will start in August or later, 2022.
The Wang lab focuses on studying the molecular basis that underlines tumor-microenvironment interaction in bone and other metastases of breast and prostate cancer. State of art facilities such as metabolomics, genomics, and sophisticated bone metastasis models are widely used in the laboratory. Multiple model systems, including Genetically Engineered Mouse Models (GEMMs), patient-derived xenograft (PDX), and syngeneic tumor models are used to address challenging mechanisms in cancer. Currently, the laboratory is stably funded by NIH and Foundation sources.
The postdoctoral position is focused on understanding the metabolic reprogramming of cancer cells in bone metastases as novel therapeutic targets. Studies will involve multiple different approaches to study tumor biology in cell and animal models, complemented by the use of genomic and metabolomic approaches.
Postdoctoral fellows will be expected to direct independent projects in a multi-disciplinary setting, assist in mentoring junior lab members, and apply for independent funding as appropriate. Multidisciplinary training in molecular biology, cellular biology and various mouse model systems including xenograft, syngeneic and transgenic mice will be offered in the postdoc training.
The search is primarily targeted towards candidates who are completing their PhD or have recently graduated with first author publications demonstrating their skills in related areas of metabolism and cancer biology. Experience of working with mouse models of cancer will be preferred. A high degree of integrity, organization and communication skills are required.
Salary is commensurate with relevant research experience and NIH pay scale.
Required qualifications (as evidenced by an attached resume):
- PhD degree in biology, biochemistry, or related field.
- At least one first-author publication in peer-reviewed journals.
- Familiar with molecular and cell biological techniques and working experience in cell culture techniques
- Working experience with mouse tumor models is preferred
- Knowledge of bioinformatics and biostatistics is preferred but not absolutely required
Interested applicants are invited to submit: 1) curriculum vitae and 2) contact information for three references to: Hai.Wang@RoswellPark.org