Postdoctoral Associate in Translational Immunology and Immunotherapy

Company
Health Research Inc. (HRI) Roswell Park Division
Department
Immunology
Hours/Shift
Full Time
Salary
Commensurate with relevant research experience and NIH pay scale
Description of Duties

The laboratory of Dr. Pawel Kalinski in the Department of Immunology is looking for a postdoctoral candidate to work on a research project aiming to identify novel ways of enhancing tumor antigen cross-presentation and induction of tumor-specific immunity by dendritic cells, with an overall goal of developing more effective immunotherapies of cancer. The selected individual will perform studies in human in vitro models (and potentially mouse in vitro and in vivo models) to study cancer cell death, antigen uptake and (cross-)presentation to CD4+ and CD8+ T cells.  The experiments will involve the analyses of immune cell functions and may involve mouse models of cancer. The ability of experimental agents and established treatments to boost immunogenic cell death, antigen presentation and the induction of anti-tumor immunity will be tested. The incumbent will be involved in preparation of scientific manuscripts and grant applications, with the expectation of developing first author papers and contributing (as a co-author) to papers of other members of the team.

Qualifications

The candidate should have a Ph.D. in immunology (or a related field), MD or MD/PhD and prior experience with commonly used laboratory methods and in vitro models to study biology of dendritic cells, T cells and cancer cells. Expertise in cancer immunology or general experience in immunotherapy (vaccines, adjuvants) and related assays is required. Experience with mouse models of cancer and immunotherapy is desirable, but not required. The candidate must be able to work independently, develop and carry out several scientific projects simultaneously, possess strong interpersonal skills, and have a proven track record of publication in the areas of cancer immunology and/or immunotherapy.

Applicant Instructions

Interested applicants are invited to submit 1) letter highlighting research interests and career goals, 2) curriculum vitae and 3) contact details for three (3) references to:
Dr. Tina Amyes, Scientific Program Manager at tina.amyes@roswellpark.org